3-Acetyl-2(3H)-oxazolone manufacturers
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| | 3-Acetyl-2(3H)-oxazolone Basic information |
| | 3-Acetyl-2(3H)-oxazolone Chemical Properties |
| Melting point | 36-38 °C | | Boiling point | 100-104 °C(Press: 16 Torr) | | density | 1.383±0.06 g/cm3(Predicted) | | pka | -3.04±0.20(Predicted) |
| | 3-Acetyl-2(3H)-oxazolone Usage And Synthesis |
| Uses | 3-Acetyloxazolin-2-one is a reagent used to synthesize (+)-(4R,5S)-5-methoxy-4-(phenylmethoxy)-2-oxazolidinone, (-)-(4S,5R)-5-methoxy-4-(phenylmethoxy)-2-oxazolidinone (I), (+)-(4R,5S)-4,5-dimethoxy-2-oxazolidinone and (-)-(4S,5R)-4,5-dimethoxy-2-oxazolidinone. | | Synthesis | The general procedure for the synthesis of 3-acetyloxazolidin-2-one from the compound (CAS:60759-48-0) is as follows: 6.80 g of 3-acetyl-5-chloro-oxazolidin-2-one was placed in a Kugelrohr distillation apparatus and distilled under reduced pressure conditions (50 mbar) and a temperature of 180°C. The product (3.80 g) was obtained from a Kugelrohr distillation apparatus. The final product 3-acetyloxazolidin-2-one (3.80 g) was obtained with a molecular weight of 127.1 g/mol (C5H5NO3). | | References | [1] Patent: US2013/345128, 2013, A1. Location in patent: Paragraph 0405; 0406 |
| | 3-Acetyl-2(3H)-oxazolone Preparation Products And Raw materials |
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