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| | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg Basic information |
| Product Name: | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg | | Synonyms: | H-HIS-SER-ASP-ALA-VAL-PHE-THR-ASP-ASN-TYR-THR-ARG-OH;HSDAVFTDNYTR;vasoactive intestinal peptide fragment*1-12 human;VASOACTIVE INTESTINAL PEPTIDE FRAGMENT 1-12 HUMAN, PORCINE, RAT;VASOACTIVE INTESTINAL PEPTIDE (1-12) (HUMAN, PORCINE, RAT);VASOACTIVE INTESTINAL PEPTIDE (1-12), HUMAN, PORCINE, RAT, OVINE;VIP (1-12), HUMAN, PORCINE, RAT;VIP (1-12), HUMAN, PORCINE, RAT, OVINE | | CAS: | 120928-03-2 | | MF: | C61H88N18O22 | | MW: | 1425.46 | | EINECS: | | | Product Categories: | peptide | | Mol File: | 120928-03-2.mol |  |
| | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg Chemical Properties |
| density | 1.56±0.1 g/cm3(Predicted) | | storage temp. | −20°C | | pka | 3.29±0.10(Predicted) |
| | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg Usage And Synthesis |
| Uses | VIP (1-12), human, porcine, rat, ovine is a vasoactive intestinal peptide (VIP) fragment. VIP (1-12), human, porcine, rat, ovine is a ligand for the CD4 (T4)/human immunodeficiency virus receptor[1][2]. | | in vivo | VIP (1-12), human, porcine, rat, ovine (1-10 μg; ICV) causes memory impairment in passive avoidance responding of the rat[1]. | Animal Model: | Male Wistar rats (250 g)[1] | | Dosage: | 1, 2.5, 5, 10 μg | | Administration: | Intracerebroventrical injection | | Result: | Caused a dose-dependent decrease in the response. |
| | References | [1] Takashima A, et, al. Vasoactive intestinal peptide (VIP) causes memory impairment in passive avoidance responding of the rat. Peptides. 1993 Oct;14(5):1067-71.
[2] Sacerdote P, et, al. Vasoactive intestinal peptide 1-12: a ligand for the CD4 (T4)/human immunodeficiency virus receptor. J Neurosci Res. 1987;18(1):102-7. DOI:10.1002/jnr.490180117 |
| | His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg Preparation Products And Raw materials |
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