Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt

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Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt Basic information
Product Name:Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt
Synonyms:sp-cgmps triethylammonium salt;sp-guanosine 3',5'-cyclic monophosphorothioate triethylammonium salt;Guanosine-3'',5''-cyclic monophosphothioate sodium salt Sp isomer;Sp-cGMPS triethylammonium salt, Sp-Cyclic 3μ5μ-hydrogen phosphorothioate guanosine triethylammonium salt;Sp-Cyclic 3′5′-hydrogen phosphorothioate guanosine triethylammonium salt;SP-GUANOSINE 3',5'-CYCLIC MONOPHOSPHOROTHIOATE TRIETHYLAMINE;SP-CYCLIC 3',5'-HYDROGEN PHOSPHOROTHIOATE GUANOSINE TRIETHYLAMINE;SP-CYCLIC 3'5'-HYDROGEN PHOSPOROTHIOATE GUANOSINE TRIETHYLAMINE
CAS:86562-10-9
MF:C10H12N5O6PS
MW:361.27
EINECS:
Product Categories:
Mol File:86562-10-9.mol
Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt Structure
Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt Chemical Properties
storage temp. −20°C
solubility H2O: 5 mg/mL
form solid
color white
Safety Information
WGK Germany 3
MSDS Information
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SigmaAldrich English
Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt Usage And Synthesis
UsesSp-cGMPS is an activator of cGMP-dependent protein kinases (PKGs). Sp-cGMPS can be used in cardiovascular disease-related research[1].
References[1] Archer SL,et al. Nitric oxide and cGMP cause vasorelaxation by activation of a charybdotoxin-sensitive K channel by cGMP-dependent protein kinase. Proc Natl Acad Sci U S A. 1994 Aug 2;91(16):7583-7. DOI:10.1073/pnas.91.16.7583
[2] Butt E, et al. Inhibition of cyclic GMP-dependent protein kinase-mediated effects by (Rp)-8-bromo-PET-cyclic GMPS. Br J Pharmacol. 1995 Dec;116(8):3110-6. DOI:10.1111/j.1476-5381.1995.tb15112.x
Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt Preparation Products And Raw materials
Tag:Guanosine-3',5'-cyclic monophosphorothioate, SP-isomer sodium salt(86562-10-9) Related Product Information
GUANOSINE-3',5'-CYCLIC MONOPHOSPHOROTHIOATE, SP-ISOMER SODIUM SALT SP-8-BR-CGMPS SP-8-pcpt-cgmps sodium salt 1-NH2-cGMP sodium salt DT-2 acetate APC1