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(+/-)5-HEPE manufacturers
- (±)5-HEPE
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- $1430.00
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2026-04-20
- CAS:83952-40-3
- Purity:
- Supply Ability: 10g
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| | (+/-)5-HEPE Basic information |
| Product Name: | (+/-)5-HEPE | | Synonyms: | (+/-)5-HEPE;(+/-)-5-HYDROXY-6E,8Z,11Z,14Z,17Z-EICOSAPENTAENOIC ACID;(+/-)5-HYDROXYEICOSA-6E,8Z,11Z,14Z,17Z-PENTAENOIC ACID;5-hydroxy-6,8,11,14,17-eicosapentaenoic acid;FTAGQROYQYQRHF-FCWZHQICSA-N;6,8,11,14,17-Eicosapentaenoic acid, 5-hydroxy-, (6E,8Z,11Z,14Z,17Z)-;5-Hydroxy-6(E),8(Z),11(Z),14(Z),17(Z)-EPA | | CAS: | 83952-40-3 | | MF: | C20H30O3 | | MW: | 318.45 | | EINECS: | | | Product Categories: | | | Mol File: | 83952-40-3.mol |  |
| | (+/-)5-HEPE Chemical Properties |
| Boiling point | 488.0±45.0 °C(Predicted) | | density | 0.997±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | 0.1 M Na2CO3: 2 mg/ml; DMF: Miscible; DMSO: Miscible; Ethanol: Miscible; PBS pH 7.2: 0.8 mg/ml | | form | Clear to light-yellow liquid. | | pka | 4.67±0.10(Predicted) |
| | (+/-)5-HEPE Usage And Synthesis |
| Description | (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites. | | Uses | (±)5-HEPE is produced by non-enzymatic oxidation of EPA. It contains equal amounts of 5(S)-HEPE and 5(R)-HEPE. The biological activity of (±)5-HEPE is likely mediated by one of the individual isomers, most commonly the 5(S) isomer in mammalian systems. EPA can be metabolized to 5-HEPE in human and bovine neutrophils, and human eosinophils, which is further metabolized to 5-oxoEPE and LTB5. The 5-series metabolites of EPA, namely 5-HEPE, 5-oxoEPE, and LTB5, have significantly decreased biological effects compared to the arachidonic acid-derived metabolites. | | Definition | ChEBI: 5-HEPE is a hydroxyicosapentaenoic acid that consists of 6E,8Z,11Z,14Z,17Z-icosapentaenoic acid with the hydroxy group located at position 5. It has a role as a mouse metabolite. It is a conjugate acid of a 5-HEPE(1-). | | References | [1] Powell, et al. Formation of a 5-oxo metabolite of 5,8,11,14,17-eicosapentaenoic acid and its effects on human neutrophils and eosinophils. J. Lipid Res. 36, 2590-2598 (1995). |
| | (+/-)5-HEPE Preparation Products And Raw materials |
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