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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide

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(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Suppliers list
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Products Intro: Product Name:Palonosetron Impurity 25
CAS:135729-78-1
Purity:0.99 Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:Palonosetron Impurity 3
CAS:135729-78-1
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Products Intro: Product Name:(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide
CAS:135729-78-1
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-34006
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Products Intro: Product Name:(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
CAS:135729-78-1
Purity:98% Package:1KG;3USD
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Products Intro: Product Name:N-(1-Azabicyalo[2,2,2]Oct-3S-Yl)-1,2,3,4-Tetrahydronaphthalen-1S-Ylcarboxamine
CAS:135729-78-1
Purity:0.99 Package:1kg,5kg,25kgs,200kgs;bulk

(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide manufacturers
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Basic information
Product Name:(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide
Synonyms:(S)-N-1-azabicyclo[2.2.0]oct-3-yl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide;(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide;Palonosetron Impurity 20;Palonosetron Impurity 27;N-(1-azabicyclo[2.2.2]octan-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxamide;Palonosetron Impurity 25;Palonosetron Impurity 1;(S)-N-(Quinuclidin-3-yl)-5,6,7,8-tetrahydronaphthalene-1-carboxaMide
CAS:135729-78-1
MF:C18H24N2O
MW:284.4
EINECS:
Product Categories:Intermediate of palonosetron hcl
Mol File:135729-78-1.mol
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Structure
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Chemical Properties
Melting point 157-159oC
Boiling point 439.2±45.0 °C(Predicted)
density 1.17
storage temp. Refrigerator
solubility Chloroform (Slightly), Methanol (Slightly)
form Solid
pka14.75±0.20(Predicted)
color White
Safety Information
MSDS Information
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Usage And Synthesis
Uses(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide is an impurity in the synthesis of Palonosetron HCl (P165800), a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide Preparation Products And Raw materials
Raw materials5,6,7,8-TETRAHYDRO-NAPHTHALENE-1-CARBONYL CHLORIDE-->5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid-->(S)-quinuclidin-3-aMine-->Oxalyl chloride
Preparation ProductsPalonosetron
Tag:(S)-N-(1-Azabicyclo[2.2.2]oct-3-yl)-5,6,7,8-tetrahydro-1-naphthalenecarboxamide(135729-78-1) Related Product Information
Formamide,Deionized Formamide Benzamide Chlorantraniliprole N,N-Dimethylformamide N,N-Diethyl-5,6,7,8-tetrahydronaphthalene-1-carboxamide 5,6,7,8-Tetrahydronaphthalene-1-carboxylic acid PLSQ-001 TM4-QJ Palonosetron Impurity 6 HCl Palonosetron Impurity 8 Palonosetron impurity Palonosetron Impurity 7 1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]- (1S)-N-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-1,2,3,4-tetrahydro-1-naphthalenecarboxaMide-d1 (3S)-AMinoquinuclidine-D1 Dihydrochloride 2-((S)-Quinuclidin-3-yl)-2,3,3a,4,5,6-hexahydro-1H-benzo[de]isoquinoline (R,S)-Palonosetron Hydrochloride (6R)-Hydroxy (R,S)-Palonosetron