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| | Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]-, (-)- Basic information |
| | Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]-, (-)- Chemical Properties |
| Boiling point | 786.8±60.0 °C(Predicted) | | density | 1.409±0.06 g/cm3(Predicted) | | pka | 4.59±0.10(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]-, (-)- Usage And Synthesis |
| Uses | (-)-JNJ-A07 is a potent and selective DENV inhibitor with an EC50 value of 31 nM[1]. | | References | [1] Bart Rudolf Romanie Kesteleyn, et al. Substituted indoline derivatives as dengue viral replication inhibitors. WO2017167951 (compound 4A) |
| | Butanoic acid, 4-[3-[[1-(4-chlorophenyl)-2-[2,3-dihydro-6-(trifluoromethoxy)-1H-indol-1-yl]-2-oxoethyl]amino]-5-methoxyphenoxy]-, (-)- Preparation Products And Raw materials |
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