| Company Name: |
LGM Pharma |
| Tel: |
1-(800)-881-8210 |
| Email: |
inquiries@lgmpharma.com |
| Company Name: |
BOC Sciences |
| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
Saredutant manufacturers
- Saredutant
-
- $289.00
-
2026-07-17
- CAS:142001-63-6
- Purity: 99.12%
- Supply Ability: 10g
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| | Saredutant Basic information |
| Product Name: | Saredutant | | Synonyms: | SR 48968;(S)-N-Methyl-N(4-(4-acetylamino-4-phenylpiperidino)-2-(3,4-dichlorophenyl)butyl)benzamide;Benzamide, N-((2S)-4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-;Benzamide, N-(4-(4-(acetylamino)-4-phenyl-1-piperidinyl)-2-(3,4-dichlorophenyl)butyl)-N-methyl-, (S)-;Sr 48968c | | CAS: | 142001-63-6 | | MF: | C31H35Cl2N3O2 | | MW: | 552.53 | | EINECS: | | | Product Categories: | | | Mol File: | 142001-63-6.mol |  |
| | Saredutant Chemical Properties |
| Boiling point | 734.7±60.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 250 mg/mL (452.46 mM) | | pka | 15.88±0.20(Predicted) | | form | Solid | | color | White to off-white |
| | Saredutant Usage And Synthesis |
| Uses | Saredutant is a selective NK2 receptor antagonist. | | in vivo | Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. Saredutant has dose-dependent effects on swim test immobility, with the low dose of 1 mg/kg having no effect and the doses of 3 and 10 mg/kg significantly reducing immobility[1]. | | IC 50 | NK2 | | References | [1] Overstreet DH, et al. Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with Desipramine in an animal model of depression. Pharmacol Biochem Behav. 2010 Aug;96(2):206-10. DOI:10.1016/j.pbb.2010.05.006 |
| | Saredutant Preparation Products And Raw materials |
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