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Rapamycin, 32-O-demethyl-

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Rapamycin, 32-O-demethyl- Basic information
Product Name:Rapamycin, 32-O-demethyl-
Synonyms:Rapamycin, 32-O-demethyl-;Rapamycin, 32-O-demethyl- (9CI);32-O-Demethyl-rapamycin DISCONTINUED;32-O-Demethyl-rapamycin;27-Desmethoxy RapaMycin;32-Desmethyl Temsirolimus;32-Desmethylrapamycin;O-Desmethyl Rapamycin
CAS:141392-23-6
MF:C50H77NO13
MW:900.16
EINECS:
Product Categories:
Mol File:141392-23-6.mol
Rapamycin, 32-O-demethyl- Structure
Rapamycin, 32-O-demethyl- Chemical Properties
Boiling point 974.8±75.0 °C(Predicted)
density 1.20±0.1 g/cm3(Predicted)
pka10.40±0.70(Predicted)
Safety Information
MSDS Information
Rapamycin, 32-O-demethyl- Usage And Synthesis
Uses27-O-Demethylrapamycin, a Rapamycin (HY-10219) derivative, is an antifungal agent. 27-O-Demethylrapamycin inhibits Candida albicans, Saccharomyces cerevisiae, and Fusarium oxysporum[1].
References[1] Wong GK, et al. Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin. J Antibiot (Tokyo). 1998 May;51(5):487-91. DOI:10.7164/antibiotics.51.487
Rapamycin, 32-O-demethyl- Preparation Products And Raw materials
Tag:Rapamycin, 32-O-demethyl-(141392-23-6) Related Product Information
Everolimus 2-Piperidinecarboxylic acid, 1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-dioxo-5-heptenyl es... 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Everolimus EP Impurity E USDOYNAPNXMXOE-SPSCNLKESA-N Everolimus Impurity 1 23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam... Everolimus Related Compound 3 EveroliMus-d4 Everolimus Related Compound 2 Seco Rapamycin Everolimus Hydrolized Impurity 28-epirapamycin Everolimus Ring-Opening Impurity 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone Rapamycin