Benzenesulfonamide, N-[(1-cyano-3-azetidinyl)methyl]- manufacturers
- NAAA-IN-2
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- $1980.00
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2026-07-27
- CAS:325775-42-6
- Purity:
- Supply Ability: 10g
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| | Benzenesulfonamide, N-[(1-cyano-3-azetidinyl)methyl]- Basic information |
| | Benzenesulfonamide, N-[(1-cyano-3-azetidinyl)methyl]- Chemical Properties |
| Boiling point | 481.9±37.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | pka | 11.11±0.40(Predicted) | | form | Solid | | color | White to off-white |
| | Benzenesulfonamide, N-[(1-cyano-3-azetidinyl)methyl]- Usage And Synthesis |
| Uses | Cathepsin K inhibitor 6 (compound 19) is an inhibitor of cathepsin K (Cat K) with an IC50 of 17 nM. Cathepsin K inhibitor 6 also has inhibitory effects on other isoforms, with IC50s of 0.05 μM (Cat L) and 0.3 μM (Cat B), respectively[1]. | | IC 50 | cathepsin L: 0.05 μM (IC50); Cathepsin B: 0.3 μM (IC50); cathepsin K: 17 nM (IC50) | | References | [1] Falgueyret JP, et al. Novel, nonpeptidic cyanamides as potent and reversible inhibitors of human cathepsins K and L. J Med Chem. 2001 Jan 4;44(1):94-104. DOI:10.1021/jm0003440 |
| | Benzenesulfonamide, N-[(1-cyano-3-azetidinyl)methyl]- Preparation Products And Raw materials |
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