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2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid Suppliers list
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| Company Name: |
Shanghai Kewel Chemical Co., Ltd.
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| Tel: |
021-64609169 18901607656 |
| Email: |
greensnown@163.com |
| Products Intro: |
Product Name:Apigenine Impurity 6
CAS:516-90-5
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| | 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid Basic information |
| Product Name: | 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid | | Synonyms: | 2-[(3α-Hydroxy-24-oxo-5β-cholan-24-yl)amino]ethanesulfonic acid;N-(3α-Hydroxy-24-oxo-5β-cholan-24-yl)taurine;Ethanesulfonic acid, 2-[[(3α,5β)-3-hydroxy-24-oxocholan-24-yl]amino]-;Taurolithocholic Acid MaxSpec? Standard;Taurolithocholic Acid D8;Taurolithocholic acidQ: What is
Taurolithocholic acid Q: What is the CAS Number of
Taurolithocholic acid;Lithocholic acid taurine conjugate;Taurodeoxycholic Acid Impurity 3 | | CAS: | 516-90-5 | | MF: | C26H45NO5S | | MW: | 483.7 | | EINECS: | | | Product Categories: | | | Mol File: | 516-90-5.mol | ![2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid Structure](CAS/GIF/516-90-5.gif) |
| | 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid Chemical Properties |
| Melting point | 212-213 °C | | density | 1.0476 (rough estimate) | | refractive index | 1.5650 (estimate) | | storage temp. | -20°C | | form | powder | | pka | 1.42±0.50(Predicted) | | color | Colorless to light yellow |
| | 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid Usage And Synthesis |
| Uses | Taurolithocholic acid is a bile acid that has the activity of increasing cell viability, inducing the S phase of the cell cycle, and promoting DNA synthesis in a concentration-dependent manner in the intrahepatic cholangiocarcinoma cell line RMCCA-1. It can also increase the phosphorylation of EGFR and ERK 1/2 and the expression of cyclin D1 in RMCCA-1 cells, and its induced RMCCA-1 cell growth can be inhibited by specific antagonists and inhibitors. | | Definition | ChEBI: Taurolithocholic acid is the bile acid taurine conjugate of lithocholic acid. It has a role as a human metabolite. It is a monocarboxylic acid amide and a bile acid taurine conjugate. It is functionally related to a lithocholic acid. It is a conjugate acid of a taurolithocholate. | | IC 50 | Human Endogenous Metabolite | | References | [1] High Frequency Technique for Continuous Recording in Chromatographic Analysis of Bile Acids |
| | 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid Preparation Products And Raw materials |
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