4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl-

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4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- manufacturers

  • EGFR-IN-46
  • EGFR-IN-46 pictures
  • $1520.00
  • 2026-07-27
  • CAS:2764772-88-3
  • Purity:
  • Supply Ability: 10g
4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- Basic information
Product Name:4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl-
Synonyms:4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl-;EGFR-IN-46
CAS:2764772-88-3
MF:C27H32F3N3O3
MW:503.56
EINECS:
Product Categories:
Mol File:2764772-88-3.mol
4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- Structure
4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- Chemical Properties
Boiling point 574.3±50.0 °C(Predicted)
density 1.26±0.1 g/cm3(Predicted)
pka9.51±0.20(Predicted)
Safety Information
MSDS Information
4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- Usage And Synthesis
UsesEGFR-IN-46 is a potent EGFR and FAK dual inhibitor with IC50s of 20.17 nM, 14.25 nM, respectively. EGFR-IN-46 significantly inhibits the growth of cancer cells. EGFR-IN-46 induces cell apoptosis[1].
IC 50EGFR: 20.17 nM (IC50); FAK: 14.25 nM (IC50)
References[1] Elbadawi MM, et al. 2-Arylquinolines as novel anticancer agents with dual EGFR/FAK kinase inhibitory activity: synthesis, biological evaluation, and molecular modelling insights. J Enzyme Inhib Med Chem. 2022 Dec;37(1):349-372. DOI:10.1080/14756366.2021.2015344
4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- Preparation Products And Raw materials
Tag:4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl-(2764772-88-3) Related Product Information
4-Piperidinamine, N-[3-[[6,7-dimethoxy-2-[4-(trifluoromethyl)phenyl]-4-quinolinyl]oxy]propyl]-1-methyl- EGFR Protein, HUMAN (621A.A, HEK293, FC) EGFR protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) HER2/CD340 protein, HUMAN (BIOTINYLATED, HEK293, HIS) HER3 Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) 2-Deoxy-D-glucose