(+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE manufacturers
|
| | (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE Basic information | | Reaction |
| Product Name: | (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE | | Synonyms: | (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE, KANATA PURITY;(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane,min.98%(S,S)-Ph-BPE;1,2-Bis[(2S,5S)-2,5-diphenyl-1-phospholanyl]ethane, 97+%;(S,S)-Ph-BPE,BPE;(S,S)-Ph-BPE;(+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane, min. 98%;(2S,5S,2'S,5'S)-1,1'-ethane-1,2-diylbis(2,5-diphenylphospholane);1,2-Bis((2S,5S)-2,5-diphenylphospholan-1-yl)ethane | | CAS: | 824395-67-7 | | MF: | C34H36P2 | | MW: | 506.61 | | EINECS: | | | Product Categories: | Chiral Phosphine;Chiral Catalysts, Ligands, and Reagents;DuPhos/BPE;Privileged Ligands and Complexes;organophosphine ligand | | Mol File: | 824395-67-7.mol |  |
| | (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE Chemical Properties |
| Melting point | 143-147 °C | | alpha | +182.7° (c 1.0, CH2Cl2) | | Boiling point | 654.2±55.0 °C(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2-8°C | | solubility | Sparingly Soluble (3.2E-5 g/L) (25°C). | | form | solid | | color | white | | Sensitive | Air Sensitive | | InChIKey | VHHAZLMVLLIMHT-LXIGBKQFNA-N | | SMILES | C([P@@]1[C@H](C2C=CC=CC=2)CC[C@H]1C1C=CC=CC=1)C[P@@]1[C@H](C2C=CC=CC=2)CC[C@H]1C1C=CC=CC=1 |&1:1,2,11,19,20,29,r| | | CAS DataBase Reference | 824395-67-7 |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids |
| | (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE Usage And Synthesis |
| Reaction |
- Phenyl-BPE exhibits enhanced activity and selectivity over existing members of the BPE ligand family in rhodium catalysed asymmetric hydrogenation.
- This ligand is highly efficient for the hydrogenation of N-acyl aryl-enamides.
- Molar substrate/catalyst ratios of up to 100,000/1 are achieved with excellent reactivity and enantioselectivity using commercial grade substrates and solvents.
- Ligand in the rhodium-catalyzed asymmetric hydroformylation of olefins.
- Ligand for asymmetric addition of allyl cyanide to ketones.
- Ligand for catalytic enantio- and diastereoselective aldol reaction of thioamides.
| | Uses | (+)-1,2-Bis((2S,5S)-2,5-diphenylphospholano)ethane is a chiral reagent that is used as a catalyst and also as an enantioselective reagent in synthetic chemistry. | | Uses | It is a DuPhos and BPE ligands which are highly efficient privileged ligands. It is a chiral phosphine ligand used in the asymmetric hydrogenation of allylic sulfoxides. | | General Description | Chiral Phosphine ligand used in the asymmetric hydrogenation of allylic sulfoxides
Dynamic Kinetic Resolution of Allylic Sulfoxides by Rh-Catalyzed Hydrogenation: A Combined Theoretical and Experimental Mechanistic Study |
| | (+)-1,2-BIS((2S,5S)-2,5-DIPHENYLPHOSPHOLANO)ETHANE Preparation Products And Raw materials |
|