| 中文名称 | Methyl 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate |
|---|---|
| 中文同义词 | |
| 英文名称 | Methyl 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate |
| 英文同义词 | Methyl 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate |
| CAS号 | 359595-95-2 |
| 分子式 | C28H28N2O4S |
| 分子量 | 488.6 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 359595-95-2.mol |
| 结构式 | ![Methyl 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate 结构式](CAS/20210305/GIF/359595-95-2.gif) |
Methyl 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate 性质
| 沸点 | 653.4±65.0 °C(Predicted) |
|---|---|
| 密度 | 1.273±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) |
| 酸度系数(pKa) | 9.64±0.40(Predicted) |
Methyl 4-[8-[[(3,4-dimethylphenyl)amino]sulfonyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate 用途与合成方法
MDM2/XIAP-IN-1 (compound 14) 是一种具有口服活性MDM2/XIAP 双靶点抑制剂。MDM2/XIAP-IN-1具有抗癌活性，IC50 值为0.3 μM，可用于癌症研究。