A 65317

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A 65317 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Qingdao Haizhi Weiyuan Biotechnology Co., Ltd.  
Tel: 18317699790 18317699790
Email: l202008112023@163.com
A 65317 Basic information
Product Name:A 65317
Synonyms:A 65317;(2R)-N1-[(1S)-2-[[(1S,2R)-1-(Cyclohexylmethyl)-2-[(5S)-3-ethyl-2-oxo-5-oxazolidinyl]-2-hydroxyethyl]amino]-1-(1H-imidazol-5-ylmethyl)-2-oxoethyl]-N4-[2-[(2-methoxyethoxy)methoxy]ethyl]-N4-methyl-2-(phenylmethyl)butanediamide (ACI)
CAS:122224-84-4
MF:C38H58N6O9
MW:742.909
EINECS:
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Mol File:122224-84-4.mol
A 65317 Structure
A 65317 Chemical Properties
Safety Information
MSDS Information
A 65317 Usage And Synthesis
UsesA-65317 is a primate-selective renin dipeptide inhibitor (IC50 of 0.37 nM) with long hypotensive response[1][2].
References[1] K M Verburg, et al. Effect of intrarenal renin inhibition on renal hemodynamics and excretory function. Am J Physiol. 1990 Jul;259(1 Pt 2):R7-14. DOI:10.1152/ajpregu.1990.259.1.R7
[2] Saul H. Rosenberg, et al. Renin Inhibitors. Integration of Pharmaceutical Discovery and Development Chapter pp 7-28.
A 65317 Preparation Products And Raw materials
Tag:A 65317(122224-84-4) Related Product Information
Z-His-Leu-OH FK 906 A 65317 Z-HIS-LYS(BOC)-OH SQ 30774 Cyclohexanebutanoicacid, a-hydroxy-b-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2R)-4-(4-morpholinyl)-2-(1-naphthalenylmethyl)-1,4-dioxobutyl]amino]-1-oxopropyl]amino]-,1-methylethyl ester, (aR,bS)-