LAS 31180 manufacturers
- LAS-31180
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- $2500.00
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2026-04-20
- CAS:137338-43-3
- Purity:
- Supply Ability: 10g
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| | LAS 31180 Basic information |
| Product Name: | LAS 31180 | | Synonyms: | LAS 31180;Methanesulfonamide, N-(1,4-dihydro-1-methyl-4-oxo-3-quinolinyl)-;LAS 31180,LAS31180;3-Methylsulfonylamino-1-methyl-4(1H)-quinolone | | CAS: | 137338-43-3 | | MF: | C11H12N2O3S | | MW: | 252.29 | | EINECS: | | | Product Categories: | | | Mol File: | 137338-43-3.mol |  |
| | LAS 31180 Chemical Properties |
| Boiling point | 386.7±52.0 °C(Predicted) | | density | 1.42±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 5.70±0.20(Predicted) |
| | LAS 31180 Usage And Synthesis |
| Uses | LAS-31180 is an inhibitor of phosphodiesterase 3, with positive inotropic and vasodilator properties. | | in vivo | In conscious chronically instrumented beagle dogs, LAS 31180 administered either by intravenous or oral route, shows a dose-dependent, long-lasting positive inotropic effect with minimal effects on heart rate. In hypertensive beagle dogs LAS 31180 elicits a potent and long-lasting fall in blood pressure[1]. | | References | [1] Gras J, et al. Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6.. . . . . DOI:10.1055/s-0031-1300321
[2] Gras J, et al. Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6. |
| | LAS 31180 Preparation Products And Raw materials |
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