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| | 4,5-Dehydro DHA Basic information |
| Product Name: | 4,5-Dehydro DHA | | Synonyms: | OXENLKNOBTVOJA-JLNKQSITSA-N;7Z,10Z,13Z,16Z,19Z-DOCOSAPENTAEN-4-YNOIC ACID;7,10,13,16,19-Docosapentaen-4-ynoic acid, (7Z,10Z,13Z,16Z,19Z)-;(7Z,10Z,13Z,16Z,19Z)-7,10,13,16,19-Docosapentaen-4-ynoic acid;4,5-DEHYDRO DOCOSAHEXAENOIC ACID;4,5-Dehydro DHA | | CAS: | 660429-97-0 | | MF: | C22H30O2 | | MW: | 326.47 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 4,5-Dehydro DHA Chemical Properties |
| solubility | 0.1 M Na2CO3: 1.7 mg/ml; DMF: >100 mg/ml; DMSO: >100 mg/ml; Ethanol: Miscible |
| | 4,5-Dehydro DHA Usage And Synthesis |
| Description | Docosahexaenoic acid (DHA; 22:6ω3) is one of the essential dietary ω-3 unsaturated fatty acids and the preferred n-3 fatty acid for development of the brain and retina.1 4,5-dehydro DHA is a novel analog of DHA in which the double bond closest to the carboxyl group has been converted into an acetylene. 4,5-dehydro DHA is a novel compound that has not been studied in biological systems. However, the corresponding acetylene in the C-20 fatty acid series (5,6-dehydro arachidonic acid) is a well known inhibitor of 5-lipoxygenase.2 | | Uses | (7Z,10Z,13Z,16Z,19Z)-Docosa-7,10,13,16,19-pentaen-4-ynoic acid is an ester product. | | Definition | ChEBI: 4,5-dehydro Docosahexaenoic Acid is a very long-chain fatty acid. | | References | 1. Anderson, G.J., Connor, W.E., and Corliss, J.D. Docosahexaenoic acid is the preferred dietary n-3 fatty acid for the development of the brain and retina Pediatr. Res. 27,89-97(1990).
2. Sok, D.E., Han, C.Q., Pai, J.K., et al. Inhibition of leukotriene biosynthesis by acetylenic analogs Biochem. Biophys. Res. Commun. 107,101-108(1982). |
| | 4,5-Dehydro DHA Preparation Products And Raw materials |
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