Company Name: |
Alabiotech Inc.
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Tel: |
001-619-354-5251 |
Email: |
sales@alabiotech-e.com |
Products Intro: |
Product Name:TAK 044 CAS:157380-72-8 Purity:>98% Package:25mg;100mg;500mg;1g;5g;10g Remarks:B0033
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Company Name: |
Alpha Biopharmaceuticals Co., Ltd
|
Tel: |
0411-39042497 |
Email: |
sales@alphabiopharm.com |
Products Intro: |
Product Name:TAK 044 CAS:157380-72-8 Purity:98% Package:1g,5g,25g,100g Remarks:B0033
|
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| TAK 044 Basic information |
| TAK 044 Chemical Properties |
Sequence | cyclo({d-Asp}-{α-amino-γ-oxo-4-phenyl-1-piperazinebutanoyl-Asp}-Asp-{d-(2-thienyl)glycine}-Leu-{d-Trp}) (disodium salt) |
| TAK 044 Usage And Synthesis |
Description | TAK-044 is an Endothelin receptor antagonist. TAK-044 arrests and reverses the development of carbon tetrachloride induced cirrhosis in rats. TAK-044 showed protective effect on neuronal cell viability in in vitro oxygen-glucose deprivation model of stroke. | Uses | TAK 044 is an antagonist of Endothelin Receptor. TAK 044 strongly inhibits ET-induced deterioration in various animal models. TAK 044 can be used in study ET-related diseases such as acute myocardial infarction,acute renal failure, acute hepatic malfunction, and subarachnoid hemorrhage[1]. | References | [1] Toshifumi Watanabe, et al. TAK-044: An Endothelin Receptor Antagonist. , 14(1), 36–46. |
| TAK 044 Preparation Products And Raw materials |
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