AChE-IN-52

AChE-IN-52 Suppliers list
Company Name: Suzhou Meidi Senuo Pharmaceutical Technology Co., Ltd.  
Tel: 13771642864
Email: snhuyu_2008@126.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
AChE-IN-52 Basic information
Product Name:AChE-IN-52
Synonyms:AChE-IN-52
CAS:2214210-63-4
MF:C24H27N3O2S
MW:421.56
EINECS:
Product Categories:
Mol File:2214210-63-4.mol
AChE-IN-52 Structure
AChE-IN-52 Chemical Properties
density 1.195±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka11.84±0.46(Predicted)
Safety Information
MSDS Information
AChE-IN-52 Usage And Synthesis
UsesAChE-IN-52 (compound A6) is an acetylcholinesterase (AChE) inhibitor. AChE-IN-52 shows antitumor efficacy, especially against breast cancer MCF-7 cells. AChE-IN-52 significantly disrupts the amino acid metabolism and inhibits migration of MCF-7. AChE-IN-52 plays anticancer role by regulating Best1 and HIST1H2BJ[1].
IC 50AChE
References[1] Shi X, et al. Identification of a 2-phenylthiazole derivative acetylcholinesterase modulator with in vitro antitumor activity in breast cancer cells. Chem Biol Drug Des. 2023 Nov 27:e14402. DOI:10.1111/cbdd.14402
AChE-IN-52 Preparation Products And Raw materials
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