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hydroxydione

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hydroxydione Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: LGC Science (Shanghai) Ltd.  
Tel: 17717235263 17717235263
Email: offer.de@lgcgroup.com
hydroxydione Basic information
Product Name:hydroxydione
Synonyms:hydroxydione;17β-(Hydroxyacetyl)-5β-androstane-3-one;5beta-dihydrodeoxycorticosterone;Pregnane-3,20-dione, 21-hydroxy-, (5β)-
CAS:303-01-5
MF:C21H32O3
MW:332.48
EINECS:
Product Categories:
Mol File:303-01-5.mol
hydroxydione Structure
hydroxydione Chemical Properties
Safety Information
MSDS Information
hydroxydione Usage And Synthesis
UsesHydroxydione is one of the chemicals studied for acute oral toxicity, repellency and hazard potential to species of wild and domestic birds.
DefinitionChEBI: A 3-oxo steroid with 5beta-configuration formed from 11-deoxycorticosterone by reduction across the C4-C5 double bond.
in vivo

Hydroxydione increases the duration of hexobarbital narcosis and repeats hexobarbital doses decrease the duration of hydroxydione narcosis[1]. Hydroxydione (5-100 mg/kg; i.v. once) produces a transient hypotension with little bradycardia and affects the respiration[2].

Animal Model:Cats with chloralose 60 to 80 mg/kg[2]
Dosage:5-100 mg/kg
Administration:Intravenous injection; 5-100 mg/kg once
Result:Produce severe respiratory depression, but showed no effect on the tibialis in response to excitation of its motor nerve under the condition of chloralose. Produced the usual substantial sustained hypotension seen in chloralosed cats to response the nictitating membrane to preganglionic excitation with a dose of 10 mg/kg. Repressed the respiration in chloralosed cats after a rapid injection.
hydroxydione Preparation Products And Raw materials
Raw materialsNADPH-->Triphosphopyridine nucleotide-->Desoxycorticosterone
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