METTL3-IN-8

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METTL3-IN-8 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
METTL3-IN-8 Basic information
Product Name:METTL3-IN-8
Synonyms:METTL3-IN-8;Urea, N-(3-methoxyphenyl)-N′-(1,2,3,4-tetrahydro-2,4-dioxo-5-pyrimidinyl)-
CAS:932512-38-4
MF:C12H12N4O4
MW:276.25
EINECS:
Product Categories:
Mol File:932512-38-4.mol
METTL3-IN-8 Structure
METTL3-IN-8 Chemical Properties
density 1.44±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka8.53±0.10(predicted)
Safety Information
MSDS Information
METTL3-IN-8 Usage And Synthesis
UsesMETTL3-IN-8 (7460-0250) is a potent METTL3 inhibitor. METTL3-IN-8 strongly ameliorates DSS-induced colitis. METTL3-IN-8 can be used Inflammatory bowel disease (IBD) research[1].
References[1] Yin H, et al. Inhibition of METTL3 in macrophages provides protection against intestinal inflammation. Cell Mol Immunol. 2024 Jun;21(6):589-603. DOI:10.1038/s41423-024-01156-8
METTL3-IN-8 Preparation Products And Raw materials
Tag:METTL3-IN-8(932512-38-4) Related Product Information
1,2-Cyclopentanediol, 3-(4-amino-5-bromo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]-, (1R,2S,3R,5R)- 4H-Pyrido[1,2-a]pyrimidine-2-carboxamide, N-[[2-[[[(3-fluorobicyclo[1.1.1]pent-1-yl)methyl]amino]methyl]-1H-indol-6-yl]methyl]-4-oxo- 1H-Isoindole-1,3(2H)-dione, 5,5′-[1,3-phenylenebis(oxy)]bis[2-(4-hydroxyphenyl)- 6-Bromo-4-[1-[[6-[(4,4-dimethyl-1-piperidinyl)methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-1H-1,2,3-triazol-4-yl]-1H-indazole WD6305 TFA 7OQL