TPP-Ce6

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TPP-Ce6 Suppliers list
Company Name: TargetMol  
Tel: 400-821-0310 15002144251
Email: xuexiang.shao@tsbiochem.com
TPP-Ce6 Basic information
Product Name:TPP-Ce6
Synonyms:TPP-Ce6
CAS:3030629-73-0
MF:C94H90N4O6P3
MW:1464.67
EINECS:
Product Categories:
Mol File:3030629-73-0.mol
TPP-Ce6 Structure
TPP-Ce6 Chemical Properties
Safety Information
MSDS Information
TPP-Ce6 Usage And Synthesis
UsesTpp-ce6 is a mitochondria-targeting photosensitizer formed by binding chlorophyll e6 (Ce6) to triphenylphosphine (TPP) via an ester bond. TPP-Ce6 can produce ROS under light irradiation, especially singlet oxygen, which can induce oxidative stress, leading to mitochondrial dysfunction and apoptosis. TPP-Ce6 can be used in the study of mitochondria in apoptosis and energy metabolism as well as cancer therapy[1].
References[1] Cao T G N, et al. Brain endothelial cell-derived extracellular vesicles with a mitochondria-targeting photosensitizer effectively treat glioblastoma by hijacking the bloodbrain barrier[J]. Acta Pharmaceutica Sinica B, 2023, 13(9): 3834-3848. DOI:10.1016/j.apsb.2023.03.023
TPP-Ce6 Preparation Products And Raw materials
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