3′,5′-diOA-dC

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3′,5′-diOA-dC Suppliers list
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
Company Name: Neobioscience Co., Ltd.  
Tel: 4006-800-892
Email: info@neobioscience.com
3′,5′-diOA-dC Basic information
Product Name:3′,5′-diOA-dC
Synonyms:3′,5′-diOA-dC
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
3′,5′-diOA-dC Structure
3′,5′-diOA-dC Chemical Properties
solubility Ethanol: 10 mg/ml
Safety Information
MSDS Information
3′,5′-diOA-dC Usage And Synthesis
Description3′,5′-diOA-dC is a ligand for the bacterial second messenger, cyclic dinucleotide, and STING agonist cyclic di-GMP (Item No. 17144) composed of oleic acid (Item Nos. 90260 | 24659) and deoxycytidine.1 It assembles with cyclic di-GMP to form supramolecular nanoparticles and has been used to deliver cyclic di-GMP in vitro and in vivo. Intravenous administration of nanoparticles composed of 3′,5′-diOA-dC and cyclic di-GMP decrease tumor weight and volume, increase the number of CD8+ T cells, neutrophils, and natural killer (NK) cells in the tumor microenvironment, and increase tumoral levels of TNF-α and IFN-γ in a B16/F10 murine melanoma model.WARNING This product is not for human or veterinary use.
References[1] LI XU, XINYUAN ZHU*   Supramolecular Cyclic Dinucleotide Nanoparticles for STING-Mediated Cancer Immunotherapy[J]. ACS Nano, 2023, 17 11: 10090-10103. DOI: 10.1021/acsnano.2c12685
3′,5′-diOA-dC Preparation Products And Raw materials
Tag:3′,5′-diOA-dC Related Product Information
c[A(2',5')pS[Rp]-A(3',5')pS[Rp]] / Rp,Rp-2'3'-c-diAMPSS 3'-dA CEP NA Piperidine, 1-methyl-4,4-bis[(9Z,12Z)-9,12-octadecadien-1-yloxy]- β-Alanine, N-[3-(1H-imidazol-1-yl)propyl]-N-[3-oxo-3-[2-(tetradecylthio)ethoxy]propyl]-, 2-(tetradecylthio)ethyl ester 1H-Indole-6-carboxamide, 1-[(2-chloro-6-fluorophenyl)methyl]-2,3-dihydro-3,3-dimethyl-2-oxo-N-[(2,4,6-trifluorophenyl)methyl]-