β-Alanine, N-[3-(1H-imidazol-1-yl)propyl]-N-[3-oxo-3-[2-(tetradecylthio)ethoxy]propyl]-, 2-(tetradecylthio)ethyl ester manufacturers
- 93-O17S
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- $793.00
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2026-07-15
- CAS:2227008-67-3
- Purity:
- Supply Ability: 10g
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| | β-Alanine, N-[3-(1H-imidazol-1-yl)propyl]-N-[3-oxo-3-[2-(tetradecylthio)ethoxy]propyl]-, 2-(tetradecylthio)ethyl ester Basic information |
| | β-Alanine, N-[3-(1H-imidazol-1-yl)propyl]-N-[3-oxo-3-[2-(tetradecylthio)ethoxy]propyl]-, 2-(tetradecylthio)ethyl ester Chemical Properties |
| Boiling point | 812.2±65.0 °C(Predicted) | | density | 1.01±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Chloroform: 100 mg/ml | | pka | 7.10±0.50(Predicted) | | form | Oil | | color | Light yellow to yellow |
| | β-Alanine, N-[3-(1H-imidazol-1-yl)propyl]-N-[3-oxo-3-[2-(tetradecylthio)ethoxy]propyl]-, 2-(tetradecylthio)ethyl ester Usage And Synthesis |
| Uses | 93-O17S is a chalcogen-containing ionizable cationic lipid used for making lipid nanoparticles (LNPs). | | Biological Activity | 93-O17S is a chalcogen-containing cationic lipidoid.1 It has been used in the synthesis of lipid nanoparticles (LPNs) for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice. LPNs containing 93-O17S have been used for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens and stimulation of interferon genes (STING) activation in a B16/F10 murine melanoma model.2 | | References | 1.Li, Y., Yang, T., Yu, Y., et al.Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteinsBiomaterials178652-662(2018)
2.Chen, J., Qiu, M., Ye, Z., et al.In situ cancer vaccination using lipidoid nanoparticlesSci. Adv.7(19)eabf1244(2021) |
| | β-Alanine, N-[3-(1H-imidazol-1-yl)propyl]-N-[3-oxo-3-[2-(tetradecylthio)ethoxy]propyl]-, 2-(tetradecylthio)ethyl ester Preparation Products And Raw materials |
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