α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride

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α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride Basic information
Product Name:α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride
Synonyms:PHENYL-2-(N-CINNAMYL-N-METHYLAMINO)PROPANOL HYDROCHLORIDE;CINNAMEDRINE HYDROCHLORIDE;CINNAMYLEPHEDRIN HYDROCHLORIDE;(±)-cinnamyl(2-hydroxy-1-methyl-2-phenylethyl)methylammonium chloride;(±)-α-[1-(Cinnamylamino)ethyl]benzyl alcohol hydrochloride;DL-Cinnamedrine hydrochloride;()-cinnamyl(2-hydroxy-1-methyl-2-phenylethyl)methylammonium chloride;α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride
CAS:25441-16-1
MF:C19H24ClNO
MW:317.85
EINECS:246-981-0
Product Categories:
Mol File:25441-16-1.mol
α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride Structure
α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride Chemical Properties
Melting point 175 °C
Safety Information
MSDS Information
α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride Usage And Synthesis
OriginatorMidol Tab,Sterling Winthrop
Manufacturing Process8.0 g of 1-phenyl-2-methylaminopropanol-1 are dissolved in 30 ml of warm benzene and the solution is mixed with 5.0 g of cinnamylbromide. It isallowed to stand for 2 h at room temperature; the whole is then filtered with suction to eliminate the phenylmethylaminopropanol hydrobromide formed and the filtrate is shaken out with dilute hydrochloric acid, while adding such a quantity of water that the thick oil drops which separate are dissolved. The aqueous extract is filtered until it is clear, rendered alkaline by means of ammonia, shaken with ether, the ether is distilled off, the residue is recrystalized, so 1-phenyl-2-methyl-cinnamylaminopropanol-1 was obtained.
In practice it is usually used as hydrochloride.
Therapeutic FunctionSmooth muscle relaxant
α-[1-(Cinnamylmethylamino)ethyl]benzyl alcohol hydrochloride Preparation Products And Raw materials
Raw materialsAmmonia-->Hydrochloric acid-->Cinnamyl bromide-->DL-Ephedrine hydrochloride
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