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| | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Basic information |
| Product Name: | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone | | Synonyms: | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone;(2S)-2,3-Dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-2-(3-hydroxy-4-Methoxyphenyl)-8-(3-Methylbut-2-en-1-yl)chroMan-4-one;5,7,3'-TRIHYDROXY-4'-METHOXY-8-P;(2S)-5,7,3'-trihydroxy-4'-methoxy-8-(3''-methylbut-2''-enyl)-flavonone;4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-, (2S)- | | CAS: | 1268140-15-3 | | MF: | C21H22O6 | | MW: | 370.4 | | EINECS: | | | Product Categories: | | | Mol File: | 1268140-15-3.mol |  |
| | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Chemical Properties |
| Boiling point | 616.0±55.0 °C(Predicted) | | density | 1.308±0.06 g/cm3(Predicted) | | solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | | form | Powder | | pka | 7.67±0.40(Predicted) |
| | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Usage And Synthesis |
| Uses | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone (compound 1), a flavonoid, is a potent ABCG2 inhibitor with an IC50 of 6.6 μM[1]. | | Definition | ChEBI: A trihydroxyflavanone that is hesperetin substituted by a prenyl group at position 8. Isolated from Macaranga conifera, it exhibits inhibitory activity against breast cancer resistance protein. | | References | [1] Muhammad Ali Versiani, et al. Flavonoids from Eight Tropical Plant Species That Inhibit the Multidrug Resistance Transporter ABCG2. J Nat Prod. 2011 Feb 25;74(2):262-6. DOI:10.1021/np100797y |
| | 5,7,3'-Trihydroxy-4'-Methoxy-8-prenylflavanone Preparation Products And Raw materials |
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