| Company Name: |
T&W GROUP |
| Tel: |
021-61551611 13296011611 |
| Email: |
contact@trustwe.com |
- IMM-H004
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- $1520.00
-
2026-04-20
- CAS:1456807-80-9
- Purity:
- Supply Ability: 10g
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| | 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)- Basic information |
| | 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)- Chemical Properties |
| Boiling point | 528.3±50.0 °C(Predicted) | | density | 1.280±0.06 g/cm3(Predicted) | | pka | 8.05±0.20(Predicted) |
| | 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)- Usage And Synthesis |
| Uses | IMM-H004, a coumarin derivative, possesses neuroprotective and potent free radical scavenging abilities. IMM-H004 significantly inhibits amyloid-β (Aβ)-induced cytotoxicity and apoptosis, offering potential value for research into neurodegenerative diseases such as Alzheimer's disease. Additionally, IMM-H004 is also capable of effectively blocking the calcium mobilization and chemotaxis induced by CKLF1-C27 (HY-P3418), thereby alleviating asthmatic pathological changes in the lung tissue of CKLF1 transgenic mice[1]. | | References | [1] Song X Y, et al. IMM-H004, a novel coumarin derivative compound, protects against amyloid beta-induced neurotoxicity through a mitochondrial-dependent pathway[J]. Neuroscience, 2013, 242: 28-38. DOI:10.1016/j.neuroscience.2013.02.049 |
| | 2H-1-Benzopyran-2-one, 7-hydroxy-5-Methoxy-4-Methyl-3-(4-Methyl-1-piperazinyl)- Preparation Products And Raw materials |
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