VER-49009

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Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:VER-49009
CAS:558640-51-0
Purity:99.99% Package:5mg;58USD|10mg;93USD|25mg;167USD
Company Name: Career Henan Chemica Co
Tel: +86-0371-86658258 +8613203830695
Email: laboratory@coreychem.com
Products Intro: Product Name:VER-49009
CAS:558640-51-0
Purity:95%-99% crystal Liu Package:1KG;0.01USD
Company Name: InvivoChem
Tel: +1-708-310-1919 +1-13798911105
Email: sales@invivochem.cn
Products Intro: Product Name:VER-49009
CAS:558640-51-0
Purity:98% Package:5mg Remarks:V0886
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354;
Email: support@targetmol.com
Products Intro: Product Name:VER-49009；CCT 129397
CAS:558640-51-0
Package:1 mL * 10mM (in DMSO)；10 mg；100 mg；2 mg；200 mg；25 mg；5 mg；50 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: Amadis Chemical Company Limited
Tel: 571-89925085
Email: sales@amadischem.com
Products Intro: Product Name:VER-49009
CAS:558640-51-0
Purity:0.97 Package:mgs,gs,kgs Remarks:A913755

VER-49009 manufacturers

  • VER-49009
  • VER-49009 pictures
  • $58.00 / 5mg
  • 2026-04-22
  • CAS:558640-51-0
  • Min. Order:
  • Purity: 99.99%
  • Supply Ability: 10g
VER-49009 Basic information
Product Name:VER-49009
Synonyms:VER-49009;VER 49009;VER49009;CS-2575;5-(5-Chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-1H-pyrazole-3-carboxamide;CCT 129397;1H-Pyrazole-3-carboxamide, 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)-;VER-49009,Inhibitor,CCT-129397,CCT129397,HSP,inhibit,VER 49009,Heat shock proteins,VER49009;VER-49009（b
CAS:558640-51-0
MF:C19H18ClN3O4
MW:387.82
EINECS:604-604-1
Product Categories:
Mol File:558640-51-0.mol
VER-49009 Structure
VER-49009 Chemical Properties
Boiling point 620.2±55.0 °C(Predicted)
density 1.379±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 100 mg/mL (257.85 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form Powder
pka7.86±0.25(Predicted)
color White to off-white
Safety Information
MSDS Information
VER-49009 Usage And Synthesis
UsesVER 49009 is a heat shock protein 90 (HSP90) inhibitor. VER 49009 causes induction of HSP72 and HSP27 alongside depletion of client proteins, including C-RAF, B-RAF, and survivin, and the protein arginine methyltransferase PRMT5.
DefinitionChEBI: 5-(5-chloro-2,4-dihydroxyphenyl)-N-ethyl-4-(4-methoxyphenyl)pyrazole-3-carboxamide is an aromatic amide obtained by formal condensation of the carboxy group of 5-(5-chloro-2,4-dihydroxyphenyl)-4-(4-methoxyphenyl)pyrazole-3-carboxylic acid with the amino group of ethylamine. It has a role as a Hsp90 inhibitor. It is a member of pyrazoles, a member of resorcinols, a member of monochlorobenzenes, a monomethoxybenzene and an aromatic amide.
in vivo

VER-49009 (4 mg/kg, i.p.) results in clear depletion of ERBB2 at 3 and 8 h following the final dose, with client protein levels returning to normal by 24 h, in the athymic mice bearing well-established OVCAR3 human ovarian ascites tumors[2].

IC 50HSP90: 25 nM (IC50)
VER-49009 Preparation Products And Raw materials
Tag:VER-49009(558640-51-0) Related Product Information
VER-246608 VER-50589 5'-O-[(4-Cyanophenyl)methyl]-8-[[(3,4-dichlorophenyl)methyl]amino]-adenosine