- SBC-110736
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- $34.00
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2026-07-13
- CAS:1629166-02-4
- Purity: 99.76%
- Supply Ability: 10g
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| | SBC110,736 Basic information |
| Product Name: | SBC110,736 | | Synonyms: | SBC110,736;N-(4-{[4-(4-Methylphenyl)-2-phenyl-1-piperazinyl]carbonyl}phenyl)acetamid;SBC110736;SBC 110736;Acetamide, N-[4-[[4-(4-methylphenyl)-2-phenyl-1-piperazinyl]carbonyl]phenyl]-;SBC-1107326(b);cholesterol,inhibit,Ser/Thr Protease,diet,Serine endopeptidases,Inhibitor,Threonine proteases,SBC 110736,SBC-110736,high,fat,Serine proteases;N-(4-(2-Phenyl-4-(p-tolyl)piperazine-1-carbonyl)phenyl)acetamide;SBC-110736, 10 mM in DMSO | | CAS: | 1629166-02-4 | | MF: | C26H27N3O2 | | MW: | 413.51 | | EINECS: | | | Product Categories: | | | Mol File: | 1629166-02-4.mol |  |
| | SBC110,736 Chemical Properties |
| Boiling point | 681.1±55.0 °C(Predicted) | | density | 1.204±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO:64.0(Max Conc. mg/mL);154.77(Max Conc. mM) | | form | A crystalline solid | | pka | 14.77±0.70(Predicted) | | color | White to off-white |
| | SBC110,736 Usage And Synthesis |
| Uses | SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1[1]. | | in vivo | SBC-110736 (male C57BL/6 mice) lowers cholesterol levels in mice that were fed high fat diet, showing a mean of 38% reduction in total cholesterol levels after two weeks relative to high fat diet animal levels and a mean 50% reduction toward return to regular diet cholesterol levels[1]. | | References | [1] Sherin Salaheldin Abdel-Meguid, et al. Anti-pcsk9 compounds and methods for the treatment and/or prevention of cardiovascular diseases. WO2014150395A1. |
| | SBC110,736 Preparation Products And Raw materials |
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