1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane

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1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane manufacturers

  • azido-mPEG3
  • azido-mPEG3 pictures
  • 2025-06-07
  • CAS:74654-06-1
  • Min. Order: 5g
  • Purity: >98.00%
  • Supply Ability: 5g
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Basic information
Product Name:1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane
Synonyms:1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane;mPEG3-Azide;N3-PEG3-O-ME;2-(2-(2-methoxyethoxy)ethoxy)ethyl azide;azido-mPEG3;1-Azido-3,6,9-trioxadecane;Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-;mPEG3-N3/Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-
CAS:74654-06-1
MF:C7H15N3O3
MW:189.2123
EINECS:
Product Categories:peg
Mol File:74654-06-1.mol
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Structure
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Chemical Properties
Boiling point 58 °C(Press: 0.01 Torr)
density 1.08 g/mL
refractive index n/D 1.4472
storage temp. 2-8°C
form liquid
color Colorless to light yellow
InChI1S/C7H15N3O3/c1-11-4-5-13-7-6-12-3-2-9-10-8/h2-7H2,1H3
InChIKeyZSSKNHYYIBAWRX-UHFFFAOYSA-N
SMILESCOCCOCCOCCN=[N+]=[N-]
Safety Information
WGK Germany WGK 3
Storage Class10 - Combustible liquids
MSDS Information
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Usage And Synthesis
Descriptionm-PEG3-azide is a PEG linker containing an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.
Usesm-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
reaction suitabilityreaction type: click chemistry
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Preparation Products And Raw materials
Preparation Products2-[2-(2-methoxyethoxy)ethoxy]ethylamine
Tag:1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane(74654-06-1) Related Product Information
O-(2-AMinoethyl)-O'-(2-azidoethyl)triethylene Glycol 17-Azido-3,6,9,12,15-pentaoxaheptadecan-1-amine m-PEG3-S-PEG1-t-butyl ester 2-[2-(2-methoxyethoxy)ethoxy]ethylamine Benzaldehyde, 4-[2-(2-methoxyethoxy)ethoxy]- Azido-PEG6 m-PEG2-Azide Azido-PEG11-amine mPEG5-N3 20-Azido-3,6,9,12,15,18-hexaoxaeicosan-1-amine m-PEG7-Azide 15-Azido-4,7,10,13-tetraoxapentadecanoic acid 13-Azido-2,5,8,11-tetraoxa-tridecane MPEG6-N3 2-[2-(2-Azidoethoxy)ethoxy]ethanamine N3－PEG36-OH 11-Azido-3 6 9-trioxaundecan-1-amine 3,6,9,12,15-Pentaoxaheptadecane-1,17-diyl bis-azide