- azido-mPEG3
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2025-06-07
- CAS:74654-06-1
- Min. Order: 5g
- Purity: >98.00%
- Supply Ability: 5g
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| | 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Basic information |
| Product Name: | 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane | | Synonyms: | 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane;mPEG3-Azide;N3-PEG3-O-ME;2-(2-(2-methoxyethoxy)ethoxy)ethyl azide;azido-mPEG3;1-Azido-3,6,9-trioxadecane;Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)-;mPEG3-N3/Ethane, 1-(2-azidoethoxy)-2-(2-methoxyethoxy)- | | CAS: | 74654-06-1 | | MF: | C7H15N3O3 | | MW: | 189.2123 | | EINECS: | | | Product Categories: | peg | | Mol File: | 74654-06-1.mol | ![1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Structure](CAS/20180703/GIF/74654-06-1.gif) |
| | 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Chemical Properties |
| Boiling point | 58 °C(Press: 0.01 Torr) | | density | 1.08 g/mL | | refractive index | n/D 1.4472 | | storage temp. | 2-8°C | | form | liquid | | color | Colorless to light yellow | | InChI | 1S/C7H15N3O3/c1-11-4-5-13-7-6-12-3-2-9-10-8/h2-7H2,1H3 | | InChIKey | ZSSKNHYYIBAWRX-UHFFFAOYSA-N | | SMILES | COCCOCCOCCN=[N+]=[N-] |
| WGK Germany | WGK 3 | | Storage Class | 10 - Combustible liquids |
| | 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Usage And Synthesis |
| Description | m-PEG3-azide is a PEG linker containing an azide group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | m-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | reaction suitability | reaction type: click chemistry | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | 1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane Preparation Products And Raw materials |
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Tag:1-azido-2-[2-(2-methoxyethoxy)ethoxy]ethane(74654-06-1)
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