| Company Name: |
Zhengzhou Acme Chemical Co., Ltd.
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| Tel: |
0371-037163312495,13303845143 13303845143 |
| Email: |
3001379618@qq.com |
| Products Intro: |
Product Name:Cariprazine D8
CAS:1308278-50-3
Purity:98% Package:5g；25g；100g；500g
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| Company Name: |
Manhag Testing Technology Co., Ltd
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| Tel: |
020-3846 2365 19110442770 |
| Email: |
458677837@qq.com |
| Products Intro: |
Product Name:Cariprazine-[d8]
CAS:1308278-50-3
Purity:1mg Package:1mg
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| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
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| Tel: |
17301488900 |
| Email: |
judy.xia@synzest.com |
| Products Intro: |
Product Name:Dehydro Aripiprazole D8 (piperazine-d8)
CAS:1308278-50-3
Purity:98% Package:1mg;5mg;10mg;100mg
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| | Cariprazine D8 Basic information |
| Product Name: | Cariprazine D8 | | Synonyms: | Cariprazine D8;[2H8]-Cariprazine;Cariprazine D8 (Piperazine-d8);Cariprazine-D8 solution | | CAS: | 1308278-50-3 | | MF: | C21H32Cl2N4O | | MW: | 427.41 | | EINECS: | | | Product Categories: | | | Mol File: | 1308278-50-3.mol |  |
| | Cariprazine D8 Chemical Properties |
| Melting point | >198°C (dec.) | | storage temp. | -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | Off-White to Pale Beige |
| WGK Germany | WGK 2 | | Storage Class | 3 - Flammable liquids | | Hazard Classifications | Acute Tox. 4 Oral
Eye Irrit. 2
Flam. Liq. 2
Met. Corr. 1 |
| | Cariprazine D8 Usage And Synthesis |
| Uses | Cariprazine-d8 is a deuterium labeled Cariprazine. Cariprazine is a novel antipsychotic agent candidate that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM). | | IC 50 | D3 Receptor | | References | [1] Seneca N, et al. Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography. Psychopharmacology (Berl). 2011 Dec;218(3):579-8. DOI:10.1007/s00213-011-2343-z |
| | Cariprazine D8 Preparation Products And Raw materials |
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