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| Product Name: | PHF6 | | Synonyms: | PHF6;L-Lysine, L-valyl-L-glutaminyl-L-isoleucyl-L-valyl-L-tyrosyl-;(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-5-amino-2-[[(2S)-2-amino-3-methylbutanoyl]amino]-5-oxopentanoyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]hexanoicacid;Hexapeptide PHF6;CENP-31;KIAA1823 | | CAS: | 329897-62-3 | | MF: | C36H60N8O9 | | MW: | 748.91 | | EINECS: | | | Product Categories: | | | Mol File: | 329897-62-3.mol |  |
| Boiling point | 1153.9±65.0 °C(Predicted) | | density | 1.210±0.06 g/cm3(Predicted) | | pka | 3.27±0.10(Predicted) | | Sequence | Val-Gln-Ile-Val-Tyr-Lys |
| Uses | PHF6 (VQIVYK) is a self-assembly sequence capable of initiating the full-length tau protein aggregation and is mapped to the third microtubule-binding repeat region of the tau protein[1]. | | References | [1] Chinmaya Panda, et al. Aggregated Tau-PHF6 (VQIVYK) Potentiates NLRP3 Inflammasome Expression and Autophagy in Human Microglial Cells. Cell. 2021 Jun 30;10(7):1652. DOI:10.3390/cells10071652 |
| | PHF6 Preparation Products And Raw materials |
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