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| | TYRPHOSTIN B48 Basic information |
| Product Name: | TYRPHOSTIN B48 | | Synonyms: | AG 494;A-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMAMIDE;A-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE;ALPHA-CYANO-(3,4-DIHYDROXY)-N-PHENYLCINNAMIDE;(E)-2-CYANO-3-(3,4-DIHYDROXYPHENYL)-N-PHENYL-2-PROPENAMIDE;N-PHENYL-3,4-DIHYDROXYBENZYLIDENECYANOACETAMIDE;TYRPHOSTIN AG 494;TYRPHOSTIN B48 | | CAS: | 139087-53-9 | | MF: | C16H12N2O3 | | MW: | 280.28 | | EINECS: | | | Product Categories: | | | Mol File: | 139087-53-9.mol |  |
| | TYRPHOSTIN B48 Chemical Properties |
| Boiling point | 586.9±50.0 °C(Predicted) | | density | 1.416±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO: soluble | | pka | 8.80±0.35(Predicted) |
| | TYRPHOSTIN B48 Usage And Synthesis |
| Uses | AG 494 is a potent inhibitor of epidermal growth factor receptor (EGF-R). AG 494 has been found to inhibit cell growth even past the restriction point when receptor activation is no longer necessary; in particular AG 494 causes cells to arrest at late G1 and and during S phase. |
| | TYRPHOSTIN B48 Preparation Products And Raw materials |
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