|
|
| | tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Basic information |
| Product Name: | tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate | | Synonyms: | tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate;1H-Benzimidazole-1-carboxylic acid, 2-amino-, 1,1-dimethylethyl ester;tert-Butyl 2-aminobenzimidazole-1-carboxylate;Hsp90-IN-37;2-amino-1H-benzo[d]imidazole-1-carboxylic acid tert-butyl ester | | CAS: | 1383133-23-0 | | MF: | C12H15N3O2 | | MW: | 233.27 | | EINECS: | | | Product Categories: | | | Mol File: | 1383133-23-0.mol | ![tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Structure](CAS/20180629/GIF/CB23308820.gif) |
| | tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Chemical Properties |
| Boiling point | 388.1±25.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | pka | 4.28±0.10(Predicted) | | form | Solid |
| | tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Usage And Synthesis |
| Uses | Hsp90-IN-37 (Z-2) is a heat shock protein 90 (Hsp90) inhibitor that inhibits Hsp90 enzymatic activity by 69%. Hsp90-IN-37 has antitumor activity[1]. | | References | [1] Abbasi M, et al. Identification of New Hsp90 Inhibitors: Structure Based Virtual Screening, Molecular Dynamic Simulation, Synthesis and Biological Evaluation. Anticancer Agents Med Chem. 2021;21(18):2583-2591. DOI:10.2174/1871520621666210201101818 |
| | tert-butyl 2-amino-1H-benzo[d]imidazole-1-carboxylate Preparation Products And Raw materials |
|