2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID

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Products Intro: Product Name:2-Bromo-4,5-dimethoxyphenylacetic acid
CAS:4697-62-5
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Products Intro: Product Name:2-Bromo-4,5-dimethoxyphenylacetic acid
CAS:4697-62-5
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CAS:4697-62-5
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Products Intro: Product Name:2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID
CAS:4697-62-5
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2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID manufacturers
2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID Basic information
Uses
Product Name:2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID
Synonyms:2-bromo-2-(3,4-dimethoxyphenyl)acetic acid;AKOS AU36-M248;6-BROMO-3,4-DIMETHOXYPHENYLACETIC ACID;2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID;RARECHEM AL BO 1516;Benzeneacetic acid, 2-bromo-4,5-dimethoxy-
CAS:4697-62-5
MF:C10H11BrO4
MW:275.1
EINECS:
Product Categories:Aromatic Phenylacetic Acids and Derivatives
Mol File:4697-62-5.mol
2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID Structure
2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID Chemical Properties
Melting point 94 °C
Boiling point 377.1±37.0 °C(Predicted)
density 1.519±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
pka4.09±0.10(Predicted)
AppearanceWhite to off-white Solid
CAS DataBase Reference4697-62-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36/37/39
HazardClass IRRITANT
HS Code 2918999090
MSDS Information
2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID Usage And Synthesis
Uses2-Bromo-4,5-methoxyphenylacetic acid is an organic intermediate. Literature reports its use in the preparation of brominated dicentrinone. Oxidized dicentrinone (DCO) exhibits leishmanic and trypanolytic activity, and DCO shows good inhibitory activity against Trypanocidal, Antitileishmanial, and rad52-repair-deficient RS322 yeast strains.
Synthesis

2-Bromo-4,5-methoxyphenylacetic acid can be obtained from 3,4-dimethoxyphenylacetic acid after bromination with bromin. 72g of 3,4-dimethoxyphenylacetic acid was dissolved in 600mL of glacial acetic acid, stirred at room temperature for 1h and then 7.2g of glacial acetic acid (60mL) solution of bromine was added, and the reaction was continued for 2h and then 200mL of ice water was added, a white precipitate was generated, filtered, and the filter cake was recrystallized with methanol to obtain 96g of the compound 2-bromo-4,5-methoxybenzeneacetic acid, with a yield of about 95%, as a white solid.

2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID Preparation Products And Raw materials
Tag:2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID(4697-62-5) Related Product Information
2-BROMO-4,5-DIMETHOXYPHENYLACETIC ACID AMINO(2-BROMO-4,5-DIMETHOXYPHENYL)ACETIC ACID (2-BROMO-4,5-DIETHOXYPHENYL)ACETIC ACID (7-BROMO-2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ACETIC ACID AKOS AU36-M431 AKOS AU36-M279 AKOS AU36-M258 AKOS AU36-M434 AKOS AU36-M278 AKOS 226-51 (2R)-2-AMINO-2-(8-BROMO(2H,3H,4H-BENZO[B]1,4-DIOXEPIN-7-YL))PROPANOIC ACID AKOS 228-19 AKOS AU36-M435 AKOS AU36-M430 AKOS AU36-M277 (2S)-2-AMINO-2-(8-BROMO(2H,3H,4H-BENZO[B]1,4-DIOXEPIN-7-YL))PROPANOIC ACID AKOS AU36-M433 AKOS AU36-M432