2-Ethyl-5-phenylisoxazolium-3'-sulfonate manufacturers
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| | 2-Ethyl-5-phenylisoxazolium-3'-sulfonate Basic information |
| | 2-Ethyl-5-phenylisoxazolium-3'-sulfonate Chemical Properties |
| Melting point | 216-219 °C (dec.) | | density | 1.3854 (rough estimate) | | refractive index | 1.4790 (estimate) | | storage temp. | Store at RT. | | solubility | insol MeCN, MeNO2, DMF, CH2Cl2; sol H2O. | | Merck | 10050 | | BRN | 4149224 | | CAS DataBase Reference | 4156-16-5(CAS DataBase Reference) |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | 2-Ethyl-5-phenylisoxazolium-3'-sulfonate Usage And Synthesis |
| Chemical Properties | white to off-white crystalline powder | | Uses | Peptide-bond former. | | Application | 2-Ethyl-5-phenylisoxazolium-3'-sulfonate is a coupling agent for peptide synthesis; protein modification; and reduction of carboxylic acids to alcohols. | | reaction suitability | reaction type: Coupling Reactions | | storage | Stable to light and temperature and nonhygroscopic. No extra precautions need to be observed. | | Purification Methods | Crystallise the reagent from diethyl ether or ethyl acetate/pet ether. [Lamas et al. J Am Chem Soc 108 5543 1986.] It is best purified by dissolving in excess of aqueous N HCl and precipitating with Me2CO to give a white fluffy solid. [Woodward et al. Tetrahedron 22 Suppl 8 321 1966, Fieser & Fieser Reagents for Organic Synthesis 1 385, 2 198.] |
| | 2-Ethyl-5-phenylisoxazolium-3'-sulfonate Preparation Products And Raw materials |
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