5-[(2R,4S)-2-(2,2-dimethylpropyl)piperidin-4-yl]-1,2-oxazol-3-one manufacturers
- AZD6564
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- $1670.00
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2026-05-11
- CAS:1251841-50-5
- Purity:
- Supply Ability: 10g
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| | 5-[(2R,4S)-2-(2,2-dimethylpropyl)piperidin-4-yl]-1,2-oxazol-3-one Basic information |
| | 5-[(2R,4S)-2-(2,2-dimethylpropyl)piperidin-4-yl]-1,2-oxazol-3-one Chemical Properties |
| | 5-[(2R,4S)-2-(2,2-dimethylpropyl)piperidin-4-yl]-1,2-oxazol-3-one Usage And Synthesis |
| Description | AZD6564 is a fibrinolysis inhibitor which acts via interference of a protein-protein interaction. | | Uses | AZD6564 is an orally active inhibitor for fibrinolysis through disruption of plasma kinase-fibrin interaction. AZD6564 dissolves human plasma clot with an IC50 of 0.44 μM. AZD6564 ameliorates hemorrhage in rats with EC50 of 1.62 μM, and exhibits good pharmacokinetic characteristics in rats[1]. | | References | [1] Cheng L, et al., Discovery of the Fibrinolysis Inhibitor AZD6564, Acting via Interference of a Protein-Protein Interaction. ACS Med Chem Lett. 2014 Feb 18;5(5):538-43. DOI:10.1021/ml400526d |
| | 5-[(2R,4S)-2-(2,2-dimethylpropyl)piperidin-4-yl]-1,2-oxazol-3-one Preparation Products And Raw materials |
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