| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:BAY-588
CAS:1799759-24-2
Purity:>=98% (HPLC) Package:5MG Remarks:SML1780-5MG
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BAY-588 manufacturers
- BAY-588
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- $917.00
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2026-04-21
- CAS:1799759-24-2
- Purity:
- Supply Ability: 10g
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| | BAY-588 Basic information |
| Product Name: | BAY-588 | | Synonyms: | BAY-588;BAY-588 >=98% (HPLC);2,4-Quinolinedicarboxamide, N4-[1-[[4-(1,1-dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-;N4-[1-[[4-(1,1-dimethylethyl)phenyl]methyl]-5-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl]-7-fluoro-2,4-quinolinedicarboxamide | | CAS: | 1799759-24-2 | | MF: | C27H25F4N5O2 | | MW: | 527.51 | | EINECS: | | | Product Categories: | | | Mol File: | 1799759-24-2.mol |  |
| | BAY-588 Chemical Properties |
| Boiling point | 603.7±55.0 °C(Predicted) | | density | 1.36±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF:20.0(Max Conc. mg/mL);37.91(Max Conc. mM)
DMSO:20.0(Max Conc. mg/mL);37.91(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);0.95(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);1.9(Max Conc. mM) | | pka | 10.37±0.70(Predicted) | | form | powder | | color | white to beige | | SMILES | FC1=CC=C2C(N=C(C(N)=O)C=C2C(NC3=C(C)N(CC4=CC=C(C(C)(C)C)C=C4)N=C3C(F)(F)F)=O)=C1 |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Aquatic Chronic 4 |
| | BAY-588 Usage And Synthesis |
| Uses | BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM[1]. | | Biochem/physiol Actions | BAY-588 is an inactive control probe for BAY-876. BAY-876 is a potent, highly selective, cell-permeable inhibitor of glucose transporter GLUT1. For characterization details of BAY-876 and BAY-588, please visit the BAY-876 probe summary on the Structural Genomics Consortium (SGC) website.BAY-876, the active GLUT1 probe, is available from Sigma. To learn more about and purchase BAY-876, click here.To learn about other SGC chemical probes for protein targets, visit sigma.com/sgc | | References | [1] Holger Siebeneicher, et, al. Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876. ChemMedChem. 2016, 11, 20. DOI:10.1002/cmdc.201600276 |
| | BAY-588 Preparation Products And Raw materials |
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