C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt)

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C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Basic information
Product Name:C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt)
Synonyms:C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt)
CAS:
MF:C73H131D3N4O31
MW:1566.871745334
EINECS:
Product Categories:
Mol File:Mol File
C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Structure
C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Chemical Properties
solubility Chloroform:
Methanol:
Water: (2:1:0.1): Soluble
Safety Information
MSDS Information
C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Usage And Synthesis
DescriptionC18 Ganglioside GM1-d3 (d18:1/18:0-d3) is intended for use as an internal standard for the quantification of C18 ganglioside GM1. Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2 C18 Ganglioside GM1 is found in the brain, primarily in the piriform cortex, amygdala nucleus, striatum, and hippocampal CA1 region.3 The ratio of C18 ganglioside GM1 (d20:1/18:0) to C18 ganglioside GM1 is decreased in the outer molecular layer of the hippocampal dentate gyrus in postmortem tissue from patients with Alzheimer’s disease.4 As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 2050]WARNING This product is not for human or veterinary use.
References[1] KOLTER T. Ganglioside biochemistry.[J]. ISRN biochemistry, 2012, 2012: 506160. DOI: 10.5402/2012/506160
[2] MOCCHETTI I. Exogenous gangliosides, neuronal plasticity and repair, and the neurotrophins.[J]. ACS Applied Nano Materials, 2005: 2283-2294. DOI: 10.1007/s00018-005-5188-y
[3] DOUGLAS A ANDRES. Spatial profiling of gangliosides in mouse brain by mass spectrometry imaging.[J]. ACS Applied Materials & Interfaces, 2020: 1537. DOI: 10.1194/jlr.ilr120000870
[4] WAKAKO HIRANO-SAKAMAKI . Alzheimer’s disease is associated with disordered localization of ganglioside GM1 molecular species in the human dentate gyrus[J]. FEBS Letters, 2015, 589 23: Pages 3611-3616. DOI: 10.1016/j.febslet.2015.09.033
C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Preparation Products And Raw materials
Tag:C18 Ganglioside GM1-d3 (d18:1/18:0-d3) (ammonium salt) Related Product Information
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