1,2,3-Propanetriol Tris(octanoate-1-13C) manufacturers
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| | 1,2,3-Propanetriol Tris(octanoate-1-13C) Basic information |
| Product Name: | 1,2,3-Propanetriol Tris(octanoate-1-13C) | | Synonyms: | GLYCERYL TRIOCTANOATE (1,1,1-13C3);GLYCERYL TRI(OCTANOATE-1-13C);TRIOCTANOIN (1,1,1-13C3);TRIOCTANOIN-CARBOXYL-13C3;TRIOCTANOIN-CARBOXYL-13C3, 98 ATOM % 13C;1,2,3-Propanetriol tris(octanoate-1-13C), Trioctanoin-carboxyls-13C3;Octanoic-1-13C acid,1,1',1''-(1,2,3-propanetriyl) ester;Octanoic-1-13C acid 1,2,3-propanetriyl ester | | CAS: | 65402-55-3 | | MF: | C27H50O6 | | MW: | 473.66 | | EINECS: | | | Product Categories: | | | Mol File: | 65402-55-3.mol |  |
| | 1,2,3-Propanetriol Tris(octanoate-1-13C) Chemical Properties |
| density | 0.970±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | refractive index | n20/D 1.447(lit.) | | Fp | >230 °F | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml | | form | An oil | | InChI | 1S/C27H50O6/c1-4-7-10-13-16-19-25(28)31-22-24(33-27(30)21-18-15-12-9-6-3)23-32-26(29)20-17-14-11-8-5-2/h24H,4-23H2,1-3H3/i25+1,26+1,27+1 | | InChIKey | VLPFTAMPNXLGLX-UTXJEHKQSA-N | | SMILES | CCCCCCC[13C](=O)OCC(CO[13C](=O)CCCCCCC)O[13C](=O)CCCCCCC | | CAS Number Unlabeled | 538-23-8 |
| WGK Germany | 3 | | Storage Class | 10 - Combustible liquids |
| | 1,2,3-Propanetriol Tris(octanoate-1-13C) Usage And Synthesis |
| Description | 1,2,3-Trioctanoyl glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2,3-trioctanoyl glycerol by GC- or LC-MS. 1,2,3-Trioctanoyl glycerol is a triacylglycerol that contains octanoic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trioctanoyl glycerol increases hippocampal levels of the glycolytic metabolites glucose 6-phosphate, fructose 6-phosphate, and β-hydroxybutyrate and the seizure threshold in the 6 Hz psychomotor seizure test in mice. Formulations containing 1,2,3-trioctanoyl glycerol have been used in cosmetic products as thickening and skin-conditioning agents. | | Uses | Tricaprilin-13C3 (Trioctanoin-13C3) is a 13C-labeled Tricaprilin (HY-B1804)[1]. Tricaprilin is an orally active and well tolerated ketogenic agent that safely induces ketosis. Tricaprilin restores brain electrical activity and metabolism to help counteract neuroinflammation in migraine. Tricaprilin is promising for research of migraine prevention and Alzheimer’s disease (AD). Tricaprilin is a pure C8 medium chain triglyceride (MCT)[1][2][3]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] Tricaprylin
[3] Kwok MK, et al. Re-thinking Alzheimer's disease therapeutic targets using gene-based tests. EBioMedicine. 2018 Nov;37:461-470. DOI:10.1016/j.ebiom.2018.10.001 |
| | 1,2,3-Propanetriol Tris(octanoate-1-13C) Preparation Products And Raw materials |
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