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| | Asp-Arg-Val-Tyr Basic information |
| Product Name: | Asp-Arg-Val-Tyr | | Synonyms: | H-Asp-Arg-Val-Tyr-OH;DRVY;ANGIOTENSIN II (1-4);ANGIOTENSIN II (1-4) HUMAN;L-Tyrosine, L-α-aspartyl-L-arginyl-L-valyl-;I(1-4)、Angiotensin II(1-4), human;Asp-Arg-Val-Tyr | | CAS: | 52580-29-7 | | MF: | C24H37N7O8 | | MW: | 551.59 | | EINECS: | | | Product Categories: | Peptide | | Mol File: | Mol File |  |
| | Asp-Arg-Val-Tyr Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | Sequence | H-Leu-Arg-Gln-Ser-Gln-Phe-Val-Gly-Ser-Arg-OH |
| | Asp-Arg-Val-Tyr Usage And Synthesis |
| Uses | Angiotensin II (1-4), human is an endogenous peptide produced from AT I by angiotensin-converting-enzyme (ACE). Angiotensin II binds the AT II type 1 (AT1) receptor, stimulating GPCRs in vascular smooth muscle cells and increasing intracellular Ca2+ levels. Angiotensin II also acts at the Na+/H+ exchanger in the proximal tubules of the kidney[1][2]. | | References | [1] De Giusti VC, et al. Modulation of the cardiac sodium/bicarbonate cotransporter by the renin angiotensin aldosterone system: pathophysiological consequences. Front Physiol. 2014 Jan 17;4:411. DOI:10.3389/fphys.2013.00411
[2] Moon JY, et al. Recent Update of Renin-angiotensin-aldosterone System in the Pathogenesis of Hypertension. Electrolyte Blood Press. 2013 Dec;11(2):41-5. DOI:10.5049/EBP.2013.11.2.41 |
| | Asp-Arg-Val-Tyr Preparation Products And Raw materials |
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