(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone

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(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone manufacturers

  • PD 81723
  • PD 81723 pictures
  • $533.00
  • 2026-05-11
  • CAS:132861-87-1
  • Purity: 99.97%
  • Supply Ability: 10g
(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Basic information
Product Name:(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone
Synonyms:(2-amino-4,5-dimethyl-3-thiophenyl)-[3-(trifluoromethyl)phenyl]methanone;PD 81,723;(2-Amino-4,5-dimethylthiophen-3-yl)(3-trifluoromethylphenyl) ketone;(3-Trifluoromethylphenyl)(2-amino-4-methyl-5-methyl-3-thienyl) ketone;4,5-Dimethyl-3-[3-(trifluoromethyl)benzoyl]-2-thiophenamine;Methanone, (2-aMino-4,5-diMethyl-3-thienyl)[3-(trifluoroMethyl)phenyl]-;(2-Amino-4,5-dimethylthiophen-3-yl)-(3-(trifluoromethyl)phenyl)methanone;(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone
CAS:132861-87-1
MF:C14H12F3NOS
MW:299.31
EINECS:
Product Categories:Adenosine receptor
Mol File:132861-87-1.mol
(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Structure
(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Chemical Properties
Melting point 100-104 °C(Solv: ligroine (8032-32-4))
Boiling point 411.7±45.0 °C(Predicted)
density 1.328±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO: ~13 mg/mL
form solid
pka-1.36±0.13(Predicted)
color yellow
Safety Information
WGK Germany 3
MSDS Information
ProviderLanguage
SigmaAldrich English
(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Usage And Synthesis
UsesPD 81,723 is an allosteric potentiator that increases the functional effects of adenosine and adenosine analogs.
Biological ActivityAllosteric potentiator at the adenosine A 1 receptor; acts via agonist-dependent and -independent mechanisms. Enhances agonist affinity for, and increased t 1/2 of dissociation from, the receptor. Also inhibits basal and forskolin-stimulated adenylyl cyclase (AC) activity in A 1 receptors expressed in CHO cells, possibly via direct potentiation of constitutive receptor activity or by direct inhibition of AC. Active in vivo .
storageStore at RT
(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone Preparation Products And Raw materials
Tag:(2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone(132861-87-1) Related Product Information
2-Amino-3-benzoyl-4,5-dimethylthiophene (2-Amino-4,5-dimethyl-3-thienyl)-[3-(trifluoromethyl)phenyl]methanone 3-(3-Methylbenzoyl)thiophene 3-Benzoylthiophene 3-(3-Trifluoromethylbenzoyl)thiophene (2-Amino-3-thienyl)(phenyl)methanone