DFP00173
(DFP-00173) manufacturers
- DFP00173
-
- $70.00 / 1mg
-
2025-05-12
- CAS:672286-03-2
- Min. Order:
- Purity: 99.15%
- Supply Ability: 10g
- DFP00173
-
- $70.00 / 1mg
-
2025-05-12
- CAS:672286-03-2
- Min. Order:
- Purity: 99.15%
- Supply Ability: 10g
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| | DFP00173
(DFP-00173) Basic information |
| Product Name: | DFP00173
(DFP-00173) | | Synonyms: | DFP00173
(DFP-00173);AQP,Inhibitor,human,isoforms,erythrocytes,selective,homologous,DFP 00173,glycerol,DFP-00173,DFP00173,inhibit,permeability;Urea, N-(2,6-dichlorophenyl)-N'-(5-nitro-3-thienyl)-;DFP00173, 10 mM in DMSO | | CAS: | 672286-03-2 | | MF: | C11H7Cl2N3O3S | | MW: | 332.16 | | EINECS: | | | Product Categories: | | | Mol File: | 672286-03-2.mol |  |
| | DFP00173
(DFP-00173) Chemical Properties |
| Boiling point | 372.1±42.0 °C(Predicted) | | density | 1.702±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 125 mg/mL (376.32 mM) | | form | Solid | | pka | 12.30±0.70(Predicted) | | color | Light yellow to yellow |
| | DFP00173
(DFP-00173) Usage And Synthesis |
| Uses | DFP00173 is a potent and selective aquaporin-3 (AQP3) inhibitor. DFP00173 inhibits mouse and human AQP3 with an IC50 of ～0.1-0.4 μM. DFP00173 is selective for AQP3 over the homologous AQP isoforms AQP7 and AQP9[1]. | | References | [1] Sonntag Y, et al. Identification and characterization of potent and selective aquaporin-3 and aquaporin-7 inhibitors. J Biol Chem. 2019 May 3;294(18):7377-7387. DOI:10.1074/jbc.RA118.006083 |
| | DFP00173
(DFP-00173) Preparation Products And Raw materials |
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