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| | BDP FL-PEG4-amine TFA salt Basic information |
| Product Name: | BDP FL-PEG4-amine TFA salt | | Synonyms: | BDP FL-PEG4-amine TFA salt;BDP FL-PEG4-amine;BODIPY FL-PEG4-amine;Boron, [N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)-5-[(3,5-dimethyl-2H-pyrrol-2-ylidene-κN)methyl]-1H-pyrrole-2-propanamidato-κN1]difluoro-, (T-4)- | | CAS: | 2183473-14-3 | | MF: | C24H37BF2N4O5 | | MW: | 510.38 | | EINECS: | | | Product Categories: | | | Mol File: | 2183473-14-3.mol |  |
| | BDP FL-PEG4-amine TFA salt Chemical Properties |
| solubility | Soluble in DMSO, DMF, DCM, low solubility in water |
| | BDP FL-PEG4-amine TFA salt Usage And Synthesis |
| Description | BDP FL-PEG4-amine TFA salt is a BDP FL linker containing an amine group and a hydrophilic PEG spacer arm. The amine group makes the compound more reactive toward carboxylic acids, NHS esters and other carbonyl groups. The hydrophilic PEG spacer arm can increase water solubility. | | Uses | BDP FL-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | BDP FL-PEG4-amine TFA salt Preparation Products And Raw materials |
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