3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide

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3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide manufacturers

  • GSK854
  • GSK854 pictures
  • $198.00
  • 2026-07-14
  • CAS:1316059-00-3
  • Purity: 98.91%
  • Supply Ability: 10g
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Basic information
Product Name:3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide
Synonyms:3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide;159344;Benzenesulfonamide, 3-[[6-[(5-chloro-2-pyridinyl)amino]-4-pyrimidinyl]amino]-4-(ethylsulfonyl)-N-methyl-;3-({6-[(5-chloropyridin-2-yl)amino]pyrimidin-4-yl}amino)-4-(ethanesulfonyl)-N-methylbenzene-1-sulfonamide;GSK854, 10 mM in DMSO;T24115
CAS:1316059-00-3
MF:C18H19ClN6O4S2
MW:482.96
EINECS:
Product Categories:
Mol File:1316059-00-3.mol
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Structure
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Chemical Properties
storage temp. Store at -20°C
solubility DMSO : 250 mg/mL (517.64 mM; Need ultrasonic)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Usage And Synthesis
UsesGSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1].
Biological ActivityGSK854 is a potent Inhibitor of Troponin I-Interacting Kinase (TNNI3K). GSK854 is a suitable lead for identifying new cardiac medicines and have been employed as in vivo tools in investigational studies aimed at defining the role of TNNI3K within heart failure[1].
References[1]. Philp J, et al. 4,6-Diaminopyrimidines as Highly Preferred Troponin I-Interacting Kinase (TNNI3K) Inhibitors. J Med Chem. 2018;61(7):3076-3088.
3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide Preparation Products And Raw materials
Tag:3-((6-((5-chloropyridin-2-yl)amino)pyrimidin-4-yl)amino)-4-(ethylsulfonyl)-N-methylbenzenesulfonamide(1316059-00-3) Related Product Information
Selonsertib BenzaMide, N-[4-[(4-ethyl-1-piperazinyl)Methyl]-3-(trifluoroMethyl)phenyl]-4-Methyl-3-[(6-Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-yl)oxy]- LL Z1640-2 1H-Indole-2-carboxamide, 6-fluoro-N-[6-[4-(1-methylethyl)-4H-1,2,4-triazol-3-yl]-2-pyridinyl]- SM1-71 Creatine phosphate