| Company Name: |
TOSUN PHARM |
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020-66392521-118 18922260391 |
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3004261881@qq.com |
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| | Pentoxazone Basic information |
| Product Name: | Pentoxazone | | Synonyms: | kpp-314;pentoxazone (bsi, pa iso);PENTOXAZONE STANDARD;Pentoxazone [iso];3-[4-Chloro-5-(cyclopentyloxy)-2-fluorophenyl]-5-(1-methylethylidene)-2,4-oxazolidinedione;3-(2'-fluoro-4'-chloro-5'-cyclopentyloxyphenyl)-5-isopropyliden-1,3-oxazolidine-2,4-dione;2,4-Oxazolidinedione,3-[4-chloro-5-(cyclopentyloxy)-2-fluorophenyl]-5-(1-methylethylidene)-;Pentoxazone Solution in Methanol, 1000μg/mL | | CAS: | 110956-75-7 | | MF: | C17H17ClFNO4 | | MW: | 353.77 | | EINECS: | | | Product Categories: | | | Mol File: | 110956-75-7.mol |  |
| | Pentoxazone Chemical Properties |
| Melting point | 98-100℃ | | Boiling point | 463.3±55.0 °C(Predicted) | | density | 1.388 | | storage temp. | 0-6°C | | pka | -2.19±0.20(Predicted) |
| | Pentoxazone Usage And Synthesis |
| Definition | ChEBI: Pentoxazone is an oxazolidinone that is 1,3-oxazolidine-2,4-dione which is substituted on the nitrogen (position 3) by a 4-chloro-5-(cyclopentyloxy)-2-fluorophenyl group, and at position 5 by an isopropylidene group. A protoporphyrinogen oxidase inhibitor, it is used as a pre- and post-emergence herbicide to control weeds in rice. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor, an agrochemical and a herbicide. It is an aromatic ether, a member of monochlorobenzenes, a member of monofluorobenzenes and an oxazolidinone. | | Production Methods | Pentoxazone is commercially produced via a process that begins with the formation of the 3-(4-chloro-2-fluorophenyl)-5-isopropylidene-1,3-oxazolidine-2,4-dione core through condensation of 4-chloro-2-fluoroaniline with ethyl 2-hydroxyisobutyrate under acidic catalysis, followed by ring closure with phosgene or triphosgene in the presence of triethylamine in dichloromethane. The key N-acylation at the oxazolidinedione nitrogen uses 3-chloromethyl-1,2,4-oxadiazole under phase-transfer conditions. Final purification via crystallisation from ethanol-water yields pentoxazone. | | Mechanism of action | Inhibition of protoporphyrinogen oxidase (PPO) - cell membrane disruption | | Pesticide Type | Herbicide |
| | Pentoxazone Preparation Products And Raw materials |
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