| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
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| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:PPIG antibody
Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
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| Company Name: |
Novus Biologicals
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| Tel: |
400821347 |
| Email: |
orders@novusbio.com |
| Products Intro: |
Product Name:PPIG Antibody
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| Company Name: |
NSJ Bioreagents
|
| Tel: |
858.663.9055 8586639055 |
| Email: |
NSJBioname@qq.com |
| Products Intro: |
Product Name:PPIG Antibody
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| Company Name: |
Enzo Biochem Inc
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| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
| Products Intro: |
Product Name:PPIG Antibody
|
| Company Name: |
Biosynth Ltd
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| Tel: |
18886812933 |
| Email: |
sales@biosynth.com |
| Products Intro: |
Product Name:PPIG antibody
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| | PPIG antibody Chemical Properties |
| | PPIG antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat | | Background | PPIG belongs to a highly conserved class of cyclophilins that function as peptidyl-prolyl-isomerases to catalyze the conversion of cis-proline to trans-proline in a polypeptide chain. PPIG contains an amino-terminal cyclophilin domain followed by Nopp140 repeats that are involved in its function as a nuclear chaperone. The carboxy-terminal of PPIG contains a SR domain that is involved in pre-mRNA splicing and processing. PPIG interacts with the carboxy-terminal domain of RNA polymerase II as well as several other SR family splicing factors. These interactions lead to changes in localization and conformation and suggest a regulatory role in transcription and pre-mRNA splicing in the elongating RNA polymerase complex. PPIG is found in the nuclear matrix and nuclear speckles and is involved in the regulation of gene expression. PPIG shows a predominantly diffuse cytoplasmic distribution at the onset of mitosis, and in late telophase the isomerase is recruited to the newly formed nuclei. | | References | [1] Fischer, G. et al. (1989) Nature 337, 476-8.
[2] Freskgård, P.O. et al. (1992) Science 258, 466-8.
[3] Nestel, F.P. et al. (1996) Gene 180, 151-5.
[4] Mortillaro, M.J. and Berezney, R. (1998) J Biol Chem 273, 8183-92.
[5] Meier, U.T. and Blobel, G. (1992) Cell 70, 127-38.
[6] Zahler, A.M. et al. (1993) Science 260, 219-22.
[7] Lin, C.L. et al. (2004) Biochem Biophys Res Commun 321, 638-47.
[8] Bourquin, J.P. et al. (1997) Nucleic Acids Res 25, 2055-61.
[9] Dubourg, B. et al. (2004) J Biol Chem 279, 22322-30. |
| | PPIG antibody Preparation Products And Raw materials |
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