| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
PD-1-IN-22 manufacturers
- PD-1-IN-22
-
- $93.00
-
2026-07-14
- CAS:2349372-98-9
- Purity: 99.51%
- Supply Ability: 10g
- PD-1-IN-22
-
- $93.00
-
2026-07-14
- CAS:2349372-98-9
- Purity: 99.51%
- Supply Ability: 10g
|
| | PD-1-IN-22 Basic information |
| Product Name: | PD-1-IN-22 | | Synonyms: | PD-1-IN-22;1,2,4-Triazolo[4,3-a]pyridine-8-carboxamide, N-[3-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-methylphenyl]-6-[[(2-hydroxyethyl)amino]methyl]-;PD 1 IN 22,PD1IN22;PD-1-IN-22, 10 mM in DMSO | | CAS: | 2349372-98-9 | | MF: | C25H25N5O4 | | MW: | 459.5 | | EINECS: | | | Product Categories: | | | Mol File: | 2349372-98-9.mol |  |
| | PD-1-IN-22 Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO |
| | PD-1-IN-22 Usage And Synthesis |
| Description | PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM[1].
IC50: 92.3 nM (programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction)[1] PD-1-IN-22 dose-dependently elevates IFN-γ secretion in a co-culture model of Hep3B/OS-8/hPD-L1 and CD3 T cells[1]. | | Uses | PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor with an IC50 of 92.3 nM[1]. | | References | [1]. Qin M, et al. Discovery of [1,2,4]Triazolo[4,3- a]pyridines as Potent Inhibitors Targeting the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction. J Med Chem. 2019 May 9;62(9):4703-4715. |
| | PD-1-IN-22 Preparation Products And Raw materials |
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