| Company Name: |
Beijing Jin Ming Biotechnology Co., Ltd.
|
| Tel: |
010-60605840 15801484223; |
| Email: |
psaitong@jm-bio.com |
| Products Intro: |
Product Name:Dimethylamine-SPDB
CAS:1193111-73-7
Package:1mg;10mg Remarks: 试剂级
|
| Company Name: |
Affinity（Wuhan）Ltd.
|
| Tel: |
15841022315 |
| Email: |
sales@affinitytech.cn |
| Products Intro: |
Product Name:Dimethylamine-SPDB
CAS:1193111-73-7
Purity:>96% Package:100mg;1g;10g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:Dimethylamine-SPDB
CAS:1193111-73-7
Package:50mg/RMB 13800
|
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| | 2-(Dimethylamino)-4-(2-pyridinyldithio)butanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester Basic information |
| | 2-(Dimethylamino)-4-(2-pyridinyldithio)butanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester Chemical Properties |
| Boiling point | 497.8±55.0 °C(Predicted) | | density | 1.38±0.1 g/cm3(Predicted) | | pka | 6.05±0.50(Predicted) |
| | 2-(Dimethylamino)-4-(2-pyridinyldithio)butanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester Usage And Synthesis |
| Uses | Dimethylamine-SPDB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. | | IC 50 | Disulfide Cleavable Linker; Cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | 2-(Dimethylamino)-4-(2-pyridinyldithio)butanoic Acid 2,5-Dioxo-1-pyrrolidinyl Ester Preparation Products And Raw materials |
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