5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

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Company Name: Shenzhen Regent Biochemical Technology Co., Ltd.  
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5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite manufacturers
5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Basic information
Product Name:5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
Synonyms:5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-uridine 3'-[2-cyanoethylbis(1-methylethyl)phosphoramidite];5'-O-DMT-5-Fluoro-2'-deoxyuridine-3'-CE phosphoramidite;5-FLUORO-DU CEP;N-blocked-5'-O-DMT CED fluorodeoxyuridine phosphoramidite;5'-DMT-5-F-2'-dU Phosphoramidite;5-fluorodeoxyuridine-ce*phosphoramidite for abi;5-FLUORODEOXYURIDINE-CE PHOSPHORAMIDITE FOR CYCLONE;Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-5-fluoro-, 3'-[2-cyanoethyl bis(1-methylethyl)phosphoramidite] (9CI)
CAS:142246-63-7
MF:C39H46FN4O8P
MW:748.78
EINECS:
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Mol File:142246-63-7.mol
5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Structure
5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Chemical Properties
storage temp. Store at -20°C
solubility DMSO: Sparingly Soluble: 1-10 mg/ml
Ethanol: Sparingly Soluble: 1-10 mg/ml
pka7.655±0.10(predicted)
Safety Information
MSDS Information
5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Usage And Synthesis
Uses5''-O-[Bis(4-methoxyphenyl)phenylmethyl]-2''-deoxy-5-fluoro-uridine 3''-[2-cyanoethylbis(1-methylethyl)phosphoramidite] is a nucleoside analog that may be effective in the treatment of breast cancer by influencing the expression of HER-2.
References[1] QUANBING MOU. DNA Trojan Horses: Self-Assembled Floxuridine-Containing DNA Polyhedra for Cancer Therapy[J]. Angewandte Chemie, 2017, 129 41: 12702-12706. DOI: 10.1002/ange.201706301
5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite Preparation Products And Raw materials
Tag:5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite(142246-63-7) Related Product Information
5'-O-(4,4'-Dimethoxytrityl)-5-fluorodeoxyuridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite 2'-O-Methyl-5-fluoro-U CEP 1-[(2'-Hydroxyethoxy)-methyl]-5-fluorouracil Dspacer CEP 3-(4,4'-Dimethoxytrityl)propandiol-1-N,N-diisopropyl (beta-cyanoethyl) phosphoramidite Floxuridine 5-Fluorouracil DMT-2'O-Methyl-rU Phosphoramidite TEGAFUR Tegafur 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine