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| | 1-Boc-1,12-diaminododecane Basic information |
| Product Name: | 1-Boc-1,12-diaminododecane | | Synonyms: | Boc-DADdec;N-t-Butyloxycarbonyl-1,12-diaminododecane;tert-butyl 2,13-diaMinotridecanoate;1,12-Diaminododecane, N-BOC protected, tert-Butyl (12-aminododec-1-yl)carbamate;Dodecane-1,12-diamine, N-BOC protected 97%;12-(tert-ButoxycarbonylaMino)dodecylaMine;N-Boc-1,12-dodecanediamine;tert-Butyl N-(12-aminododecyl)carbamate | | CAS: | 109792-60-1 | | MF: | C17H36N2O2 | | MW: | 300.48 | | EINECS: | | | Product Categories: | pharmacetical | | Mol File: | 109792-60-1.mol |  |
| | 1-Boc-1,12-diaminododecane Chemical Properties |
| Melting point | 84-86 °C | | Boiling point | 409.2±18.0 °C(Predicted) | | density | 0.924±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C(protect from light) | | form | solid | | pka | 12.94±0.46(Predicted) | | color | Pale yellow |
| Hazard Codes | Xi | | Hazard Note | Irritant | | HS Code | 2924190090 |
| | 1-Boc-1,12-diaminododecane Usage And Synthesis |
| Description | tert-Butyl (12-aminododecyl)carbamate can be used as a PROTAC linker in the synthesis of PROTACs. tert-Butyl (12-aminododecyl)carbamate is an alkane chain with terminal amine and Boc-protected amino groups. Amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The Boc group can be deprotected under mild acidic conditions to form the free amine. | | Uses | 12-(tert-Butoxycarbonylamino)dodecylamine can be used to synthesize inhibitors of topoisomerase I for use as anticancer agents. | | IC 50 | Alkyl/ether |
| | 1-Boc-1,12-diaminododecane Preparation Products And Raw materials |
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